1、Alpha, Eye Movements, Steering & Lane PositionPsychiatric illnessInsomniaOSASDaytime sleepinessFatigue Attention, concentration and memory impairment Sleep disturbances AccidentsImpaired quality of lifeMedical consequencesAbsenteeism, Health care utilizationNORMIHCIH*Sjostrom et al.Thorax 2003Logan
2、et al.J. Hypertension 2001Javaheri et al.Circulation 1999Schafer et al.Cardiology 1999 Sanner et al.Clin Cardiology 2001 Somers et al.Circulation 2004Franklin KA et al Lancet 2005;345:1085-7p0.05p0.01未治疗未治疗OSA病人的房颤复发率增加病人的房颤复发率增加Milleron et al Eur Heart J 2004内分泌疾病内分泌疾病肢端肥大症：多伴有多伴有SAHS, 阻塞性和中枢性兼有。可见
3、口阻塞性和中枢性兼有。可见口咽部肌肉组织和舌体肥大。咽部肌肉组织和舌体肥大。甲状腺功能减退症：造成造成舌体肥大舌体肥大, ,悬雍垂、软腭和舌根悬雍垂、软腭和舌根松弛松弛, , 口咽部狭窄、上气道塌陷气道阻塞。口咽部狭窄、上气道塌陷气道阻塞。糖尿病：糖尿病患者中糖尿病患者中SAHS SAHS 发病率是普通人群发病率是普通人群3 34 4倍。倍。可能与糖尿病的血管神经病变损害呼吸中枢及呼吸肌有关。可能与糖尿病的血管神经病变损害呼吸中枢及呼吸肌有关。柯兴综合征：常伴有睡眠呼吸障碍，伴睡眠呼吸障碍患者常伴有睡眠呼吸障碍，伴睡眠呼吸障碍患者白天嗜睡更明显。白天嗜睡更明显。Prevalence of sl
4、eep apnea in acromegaly in two cohorts in Sydney, Australia. In hospital 1, which has a sleep laboratory, almost all patients with acromegaly肢端肥大症 have sleep apnea. In hospital 2, a regional endocrine center without sleep investigation facilities, 60% of patients have sleep apneaInsulin sensitivity index (ISI) at baseline, 2 days, and 3 months after onset of continuous positive airway pressure (CPAP) treatment in 31 patients.
