1、作者：Larry Firkins, DVM, MS, MBAUniversity of IllinoisCollege of Veterinary Medicine美国伊利诺斯大学兽医学院Economic Cost of Disease疾病的经济损失Death Loss 死亡损失Obviously Sick Pigs 明显的病猪Treatment Costs治疗开支Lost Production生产损失Lost Access to Markets 市场的丧失 Organisms such as bacteria, viruses, etc., that can cause disease ar
2、e called Pathogens.细菌，病毒等引起疾病的微生物称为病原 Not all microorganisms are pathogenic.并非所有微生物都有致病性 Some are opportunists.有些是条件性病原体 Some are non-pathogenic, some are helpful.有些为非致病性的，有些则有益Ab level 抗体水平Infection感染0 7 14 21 .0 7 14 21 .Ab level 抗体水平Infection感染0 7 14 21 .Ab level 抗体水平Infection感染0 7 14 21 .Ab leve
3、l 抗体水平Infection感染抗体水平感染0 7 14 21 .Maternal Ab typically lasts for 3-4 weeks.母源抗体一般持续34周Immunodeficient Sowor Poor Colostrum IntakeVaccinated SowUnvacc. SowBirth 3 weeksImmunity免疫缺陷的母猪，或初乳摄入不足周PRV Ab lasts upto 16 weeks.伪狂犬病母源抗体可持续16周Immunodeficient Sowor Poor Colostrum IntakeVaccinated SowUnvacc. So
4、wBirth weeks免疫缺陷的母猪，或初乳摄入不足Ab response after single vaccination一次免疫接种后的抗体应答Booster Effect强化效果母原抗体干扰Maternal AbInterference免疫缺陷的母猪，理想免疫模式为在被动免疫消失前激活主动免疫Combined Maternal and Active ImmunityHealthSicknessHealth and prosperityDisease and Economic LossHeavy ExposureImmunity not EnoughExposureVery HighHi
5、ghLowImmunity免疫缺陷的母猪，ExposureVery HighHighLowImmunity免疫缺陷的母猪，Window ofOpportunity免疫缺陷的母猪，Segregation, Isolation, Sanitation, Immunization分离，隔离，卫生，免疫Separate sick pigs from healthy将病猪与健康猪隔离Use logical and effective sanitation进行合理有效的卫生消毒strong chemicals强效药剂Better Environments 环境管理Use controlled exposure + vaccines 有控制地接触病原免疫接种 Diagnosis诊断Periodic review of the program方案的阶段性总结
