1、Intestinal Taeniasis and cysticercosis 肠绦虫病肠绦虫病Intestinal Taeniasis病原学病原学猪带绦虫猪带绦虫 Taenia solium Taenia solium 牛带绦虫牛带绦虫 Taenia saginata Taenia saginata 短膜壳绦虫短膜壳绦虫 Hymenolepis nana Hymenolepis nana 长膜壳绦虫长膜壳绦虫 Hymenolepis diminuta Hymenolepis diminuta 阔节裂头绦虫阔节裂头绦虫 Diphyllobothrium latumDiphyllobothrium
2、 latum犬复孔绦虫犬复孔绦虫 Dipylidium caninumDipylidium caninumMorphology Adult tapeworms have three Adult tapeworms have three major parts:major parts:The scolex The scolex The neck The neck The proglottids The proglottids tegument microvillitegument microvilli Two muscle layersTwo muscle layers The nervous
3、system The nervous system The excretory systemThe excretory system There is no digestive systemThere is no digestive system Male and female gonadsMale and female gonadsMorphology of proglottids Characteristics of T.saginata and T.solium T.saginata T.Soliumscolex big small square ball 4 suckers 4 suc
4、kers no hooks rostellum with hooksSegment 1000-2000 1000 Length 4-8m 2-4mEgg radially striate radially striateMature segmentOvary 2 large lobes 1 small and 2 largeGravid segment Uterine branch 15-30 7-12 Life cycleLife cycle EpidemiologyEpidemiology 传染源:传染源:病人病人 传播途径:食入传播途径:食入 人群易感性:普遍人群易感性:普遍 流行情况:
5、流行情况:Pathogenesis obstructionobstruction tissue invasion tissue invasion Clinical Picture subclinicalsubclinical The finding of proglottids The finding of proglottids fullness,diarrhea,constipation,fullness,diarrhea,constipation,appetite.appetite.流行病学史流行病学史 临床表现临床表现 实验室检查实验室检查 卵卵EggsEggs 节片节片graved
6、proglottidgraved proglottid 头节头节scolexscolex诊断诊断 治疗治疗 吡喹酮吡喹酮 15-20mg/kg once15-20mg/kg once 阿苯达唑阿苯达唑 800mg/d 3d800mg/d 3dChildren and pigs in the village of Huancyao in Peru,an area of high cysticercosis transmission预防预防 管理传染原:治疗病人管理传染原:治疗病人 防止猪牛的感防止猪牛的感染染 切断传播途径:含囊尾蚴的肉切断传播途径:含囊尾蚴的肉 囊虫病Cysticercosis
7、病原学病原学猪囊尾蚴猪囊尾蚴流行病学流行病学 传染源传染源 Patients with T.SoliumPatients with T.Solium 传播途径传播途径 accidental ingestion of eggs from accidental ingestion of eggs from patients harbouring the adult wormpatients harbouring the adult worm retro-infection retro-infection 人群易感性人群易感性 流行情况流行情况临床表现临床表现 脑囊虫病脑囊虫病 皮下及肌肉囊虫病皮下及肌肉囊虫病 眼囊虫病眼囊虫病 其他其他诊断诊断 Blood CSF Immunological test X ray CT MRI Biopsy治疗治疗 阿苯达唑(阿苯达唑(AlbendazoleAlbendazole)18-20mg/kg/day,1018-20mg/kg/day,10 吡喹酮(吡喹酮(pyquitonpyquiton)40-60mg/kg/day,340-60mg/kg/day,3 甘露醇甘露醇 镇静药镇静药注意事项注意事项预防预防 驱绦灭囊驱绦灭囊 禁止米猪肉上市禁止米猪肉上市 粪便管理粪便管理