器官移植的发展与未来课件.ppt

1、2023-1-29器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来Human chimera,or“homo novo.”Mans original structure has been modified so that he can accept an organ“from elsewhere”器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来Prof.V.Demikhov and his two-headed dog.photo taken two days after the operation U.S.S.R(1950)器官

2、移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来Boronios sheep(1804).Successful replacement skin grafts on the back of an ewe.器官移植的发展与未来Paul Bert next to Claude Bernard,performing a vivisection procedure in his laboratory at the College of France in 1889.器官移植的发展与未来Free split-skin graft on a burn of the should

3、er and arm.器官移植的发展与未来THE KIDNEY:A PILOT ORGAN器官移植的发展与未来 At the Vienna Medical Society meeting held in January 1902,the surgeon Emerich Ullmann reported the first case of renal transplantation performed in the neck of a dog.The ureter,brought out to the skin,oozed a“liquid which resemble urine”over a

4、 period of five days.器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来nIn 1933,the russian surgeon Voronoy(1896-1961)performed the first homologous renal transplantation in man using a human cadaver kidney.器官移植的发展与未来Serge Voronoff,at the Collge de France.Testicular transplantation from a monkey to man.A retired indian

5、 army colonel in fine form after the operation.器官移植的发展与未来nA young woman was in profound coma with anuria for 10 days following an abortion complicated by acute tubulopathy due to septic shock and incompatible transfusion.David M.Hume(1917-1973)器官移植的发展与未来Mrs Renard and her son Marius to whom she dona

6、ted a kidney in December 1952.Pelvic implantation of the kidney with restoration of the urinary tract.器官移植的发展与未来John Merrill and Joseph Murry(Nobel Prize 1991)at the Brigham in 1953First susccessful transplantation between two identical twins in 1954 by the Murry,Merrill and Harrison team.器官移植的发展与未来

7、Peter Brian Medawar,Nobel Prize in 1960.Rejection was by the action of lymphocytes which described as“immunocomeptent cells“器官移植的发展与未来(Jean Dausset,Nobel Prize in 1980)(Human MHC)器官移植的发展与未来“Sam”and“Honest John”器官移植的发展与未来Mrs Gen and her donor at Foch Hospital in 1960器官移植的发展与未来Marianne Mattlaer with“M

8、ana”,who received a kidney in 1960 with immunosuppression by azathioprine,with a litter tow years after the transplantation.器官移植的发展与未来The primitive fungus from which cyclosporine is extracted(Tolypocladium inflatum)Sir Roy Calne器官移植的发展与未来 William J.Kolff,father of the artificial kidney and heart.The

9、 first artificial kidney designed by Kolff in 1945.器官移植的发展与未来“The centre effect”:Terasaki and statistics器官移植的发展与未来Falkert O.Belzer.The first human kidney preserved on a perfusion machine prior to transplantation in August 1967.器官移植的发展与未来器官移植的发展与未来Thomas Starzl in the operating room on March 1,1963,p

10、erformed the first liver transplantation,the recipient survived five hours after the transplantation.器官移植的发展与未来Oil painting by Sir Roy Calne(1990)represent a phase of liver transplantation coordinated by the entire surgical team.器官移植的发展与未来Richard Lillehei器官移植的发展与未来Denise Darvall,the first human hear

11、t”donor”Louis Washkansky,the heart recipient.December 3,1967.Christiaan N.Barnard,cardiovascular surgeon at Capetown.器官移植的发展与未来器官移植的发展与未来James D.Hardys team,performed the first human lung transplantation on June 11,1963,seven and a half months before they performed the first human heterologus heart

12、transplantation.器官移植的发展与未来The first blood transfusion from animals to man were attempted in 1628.器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来王良順教授，台北榮總呼吸加護病房主任王良順教授，台北榮總呼吸加護病房主任器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来SMASAEIAIIACIA器官移植的发展与未来PVDuodenum graftY-graft a.Pancreas graft器官移植的发展与未来Pancreas器官移植的发展与未来Pancreatico-Duodenal graftKidney graftJejunum器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来器官移植的发展与未来2023-1-29器官移植的发展与未来