1、蚊叮咬蚊叮咬随唾液入人体随唾液入人体肝肝C C胀破胀破(肝肝)(速发型和迟发型速发型和迟发型)红外期裂殖子红外期裂殖子环状体环状体大滋养体大滋养体未成熟裂殖体未成熟裂殖体810h配子体配子体成熟裂殖体成熟裂殖体红内期红内期裂殖子裂殖子RBC薛氏小点薛氏小点蚊蚊叮咬叮咬吸血入胃吸血入胃(唾液腺唾液腺)()录像Ruptured oocystRelease of sporozoitesSporogonic cycleMacrogametocyteOokineteOocystLiver cellInfected liver cell Exo-erythrocytic CycleRuptured sch
2、izontschizontMosquito takes a blood mealInfective stageDiagnostic stageExflagellated microgametocyteMicrogamete entering macrogameteRuptured schizontschizontErythrocytic CycleMature Tropho-zoite Gametocytes ring stageGametocytes(猫粪猫粪)(动物肉类等动物肉类等)猫食入猫食入入肠上皮细胞入肠上皮细胞猫食入猫食入入肠上皮细胞入肠上皮细胞Fecal OocystsTissu
3、e Cysts Both oocysts and tissue cysts transform into tachyzoites shortly after ingestion.Tachyzoites localize in neural and muscle tissue and develop into tissue cyst bradyzoites.If a pregnant woman becomes infected.Tachyzoites can infect the fetus via the bloodstream.I=Infective Stage D=Diagnostic Stage Serum.CSFDiagnostic Stage 1)Serological diagnosis2)Direct identification of the parasite from peripheral blood,amniotic fluid,or in tissue sections.先天性弓形虫病无脑儿先天性弓形虫病脑积水先天性弓形虫病小脑儿