1、Age-related diseases and cancer COENZYME ICOENZYME I2022-7-282022-7-282022-7-28Eric Verdin.(2015).Special Section 350（6265）:1208-1213.NAD biosynthetic pathways and metabolism in different cellular compartments.2022-7-282022-7-28E F.Fang,.(2017).NAD+:a key metabolic regulator with great therapeutic p
2、otential:1120-1143.NAD availability can influence the activity of three groups of master regulator enzymesthe sirtuins,the PARPs and cyclic ADP-ribose synthases.Each group of enzymes regulate many biological processes and can thus couple changes in NAD levels with a wide range of physiological respo
3、nses.2022-7-282022-7-281980s1980s1930s1930sAge-related diseases and cancer could be the consequence of a decline in NAD+concentrationsAmanda Garrido(2017).Trend in cancer 181:181-199.Metabolic syndrome including cardiovascular disorders,type 2 diabetes and obesity,Neurodegenerative diseases such as
4、Alzheimer and Parkinsondiseases,arthritis,and osteoporosis,and cancer are some of the diseases that commonly affect human health during aging.2022-7-282022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28GSulta
5、ni.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-282022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28GSultani.(2017).Trends in Molecular Medicine23（10）:900-9182022-7-28TheEnd2022-7-28
