1、Liu Fu-You MD.(1)kidney L T11L2 R T12L310cm in length5cm in width4cm in thickness134 148g in weight(1)kidney(2)Renal Cortex renal cortex 8090%of glomerulus Glomerular capsule renal medulla renal tubule(3)Glomerulus Glomerular Filtration Membrane endothelial cells basement epithelial cells(4)Renal tu
2、bule proximal convolute reabsorption distal convolute regulating of acid-base balanceRenal tubular diseases(renal,tubular,acidosis)Type(dRTA)Type(pRTA)+(5)Renal InterstitiumInterstitial cellsFibrocyteExtracelluar matrixPathogenic microorganismimmunoreactionAcute interstitial nephritisChronic interst
3、itial nephritisInterstitium(6)Renal Pelvis,Ureter Pathogenic microorganism(upper urinary tract)(7)Urinary Bladder,UrethraUrinary bladderUrethra(Lower urinary tract)Pathogenicmicroorganism 4(proteinuria3.5g/day)4Proteinuria+nephrotic syndrome proteinuria150mg/24hrglomerular tubular overflow secretory
4、 or1.5g/24hr 1.5g/24hr immunoglobulin histic2-microglobulinInfectiontoxicity Bence JonesproteinmyelomaSelective(albumin)NonSelective(mixture)Dysmorphic Rbc Hemogeneous RbcCalculus,tumor,TB,infectionGlomerular diseaserenal parenchymaRenal vesselArleriae renalis stenosisvolume dependentrenin dependent
5、EdemaGlomerular Filtrate Rate(GFR)Plasma colloid osmotic pressure AnasarcaLocal edemaLower extremity edemaCommon Clinical Laboratory Assessment of Renal DiseaseCell protein cast glomerular tubular IVP CT renal biopsy MRI Cr Ccr GFR PSP MosthsRenal diseaseurinalysisRenal functionSpecial examinationRemoval causesCorticosteroidImmunosuppressiveSymptomatic and supportingAnti-inflammatoryChinese herbsRenal failure dialysis HD PD
