1、小儿睡眠呼吸暂停Nelson 儿科学,17版,2007;99小儿睡眠呼吸暂停2Nelson 儿科学,17版,2007;99小儿睡眠呼吸暂停3Nelson 儿科学,17版,2007;99小儿睡眠呼吸暂停4 WATERS K A,Am J Med Genet,1995,59(4):460-466.小儿睡眠呼吸暂停5小儿睡眠呼吸暂停6Hsueh-yu L,Chang Gung Med J,2009;32:24757小儿睡眠呼吸暂停7AMERICAN THORACIC SOCIETY.Am J Respir Crit Care Med,1996,153(2):866-878.小儿睡眠呼吸暂停8 AME
2、RICAN THORACIC SOCIETY.Am J Respir Crit Care Med,1996,153(2):866-878.OSAS in children is a disorder of breathing during sleepcharacterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction(obstructive apnea)that disrupts normal ventilation during sleep and normal
3、 sleep patterns.It is associated with symptoms including habitual(nightly)snoring,sleep difficulties,and/or daytime neurobehavioral problems.Complications may include growth abnormalities,neurologic disorders,and cor pulmonale,especially in severe cases.Various risk factors have beenidentified and a
4、re defined.小儿睡眠呼吸暂停9小儿睡眠呼吸暂停10小儿睡眠呼吸暂停11Carolyn E I-L,AJRCCM,2007;175:436441小儿睡眠呼吸暂停12小儿睡眠呼吸暂停13小儿睡眠呼吸暂停14小儿睡眠呼吸暂停15小儿睡眠呼吸暂停16小儿睡眠呼吸暂停17小儿睡眠呼吸暂停18Oscar S C,Proc Am Thorac Soc,2008;5:274282小儿睡眠呼吸暂停19Oscar S C,Proc Am Thorac Soc,2008;5:274282Kahn A,Sleep,1993;16:409413Crouzon syndrome小儿睡眠呼吸暂停20Oscar S
5、 C,Proc Am Thorac Soc,2008;5:274282小儿睡眠呼吸暂停21Oscar S C,Proc Am Thorac Soc,2008;5:274282小儿睡眠呼吸暂停22小儿睡眠呼吸暂停23小儿睡眠呼吸暂停24小儿睡眠呼吸暂停25小儿睡眠呼吸暂停26小儿睡眠呼吸暂停27小儿睡眠呼吸暂停28蒙逖航,医学综述,2008;14(20):31413143小儿睡眠呼吸暂停29OSA引起心血管事件的细胞学机制小儿睡眠呼吸暂停30小儿睡眠呼吸暂停31Athanasios G,Chest,2008;134:324331小儿睡眠呼吸暂停32小儿睡眠呼吸暂停33A,adenoid;N,na
6、sopharyngeal measurement;P,pharyngeal measurement;T,tonsil.T/P 0.479提示中重度OSA。A/N 0.74以上A M Li,Arch Dis Child 2002;87:156159小儿睡眠呼吸暂停34小儿睡眠呼吸暂停35小儿睡眠呼吸暂停36 Liner LH,Curr Opin Pediatr,2006,18(3):272-276.小儿睡眠呼吸暂停37S L Verhulst,Arch Dis Child 2006;91:233237小儿睡眠呼吸暂停38Marcus CL,Pediatr Pulmonol,1992;13:162
7、1Biban P,Pediatrics,1993;92:461463小儿睡眠呼吸暂停39Brouillette R,J Pediatr.1984;105:1014小儿睡眠呼吸暂停40小儿睡眠呼吸暂停41小儿睡眠呼吸暂停42小儿睡眠呼吸暂停43小儿睡眠呼吸暂停44小儿睡眠呼吸暂停45小儿睡眠呼吸暂停46William WH,Pediatrics Current diagnosis&Treatment,19th ed,2009;467小儿睡眠呼吸暂停47小儿睡眠呼吸暂停48McColley S,Arch Otolaryngol Head Neck Surg,1992;118(9):940943Go
8、ldberg S,Pediatr Pulmonol,2005;40(3):205210Rosen GM,Pediatrics,1994;93(5):784788小儿睡眠呼吸暂停49Gorur K,Int J Pediatr Otorhinolaryngol,2001,59(1):41-46.Basha S,Laryngoscope,2005,115(6):1101-1103.Mitchell Int JPediatrOtorhinolaryngol,2004,68(11):1375-1379.小儿睡眠呼吸暂停50小儿睡眠呼吸暂停52张亚梅,王桂香.中国全科医学,2007,10(2):102-1
9、04.年幼儿因颅面生长快年幼儿因颅面生长快,应每应每6 6月评价月评价1 1次次小儿睡眠呼吸暂停53Massa F,Arch Dis Child,2002;87:438443小儿睡眠呼吸暂停54FT 失败例ST 成功例不同年龄段nCPAP的成功率Massa F,Arch Dis Child,2002;87:438443小儿睡眠呼吸暂停55Craig AH,Neuropsychi Dis Treat,2006;2(3):30926小儿睡眠呼吸暂停56Craig AH,Neuropsychi Dis Treat,2006;2(3):30926小儿睡眠呼吸暂停57 Hoban TF,Neurologist,2005,11(6):325-337.小儿睡眠呼吸暂停58Aviv DG,Am J Respir Crit Care Med,2005,172;364370小儿睡眠呼吸暂停59小儿睡眠呼吸暂停60小儿睡眠呼吸暂停61小儿睡眠呼吸暂停62小儿睡眠呼吸暂停63Raanan A,Am J Respir Crit Care Med,2005,172;264265小儿睡眠呼吸暂停64谢谢您的关注!小儿睡眠呼吸暂停65