动脉粥样硬化动脉粥样硬化管壁增厚变硬、失去弹性、官腔缩小管壁增厚变硬、失去弹性、官腔缩小(从内膜开始从内膜开始)脂质、胶元纤维、弹性纤维、钙质沉着、蛋白多糖等结缔组织基质形成,斑块呈黄脂质、胶元纤维、弹性纤维、钙质沉着、蛋白多糖等结缔组织基质形成,斑块呈黄色粥样。(中层)色粥样。(中层)PTCA的机制的机制A.A.The First Patient to Undergo Coronary Angioplasty38-year-old manCoronary Angiogram Before PTCA(1977-9-16)23-year Follow-up after PTCA(2000-4-10)NEJM,2001;344(2):144-145GruentzigThank You!