颅脑先天畸形完美版课件.pptx

1、 offline browser(Unregistered)on 09/13/07 10:15:08.Address:Title:PowerPoint Presentation Size:6165 Last Modified:Thu,15 Jun 2006 02:07:48 GMT本节应了解、熟悉和掌握的知识点了解颅脑先天发育异常的分类 熟悉常见颅脑发育异常的影像学表现 神经皮肤综合征的影像学表现 offline browser(Unregistered)on 09/13/07 10:15:08.Address:Title:PowerPoint Presentation Size:5554 L

2、ast Modified:Thu,15 Jun 2006 02:07:48 GMT本节学习中的难点脑先天性发育异常的分类和影像学表现 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:3628 Last Modified:Thu,15 Jun 2006 02:07:58 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size

3、:2851 Last Modified:Thu,15 Jun 2006 02:07:48 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4811 Last Modified:Thu,15 Jun 2006 02:07:48 GMT颅缝提早骨化、闭合，致头颅畸形，包括舟状 头畸形、短头畸形、尖头畸形、偏头畸形、小 头畸形等 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:

4、PowerPoint Presentation Size:5317 Last Modified:Thu,15 Jun 2006 02:07:50 GMT矢状缝及顶颞缝提早闭合，头颅左右径生长受限，前后径生长显著 舟状头变形 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:5582 Last Modified:Thu,15 Jun 2006 02:07:56 GMT 颅底陷入枕骨大孔周围骨质，枕骨基底部、髁部、鳞部向颅腔内陷入 扁平颅底前、中、后颅窝失去正常的

5、阶梯状关系结节性硬化（tuberous sclerosis）扁平颅底前、中、后颅窝失去正常的阶梯状关系病因：先天性，后天性offline browser(Unregistered)on 09/13/07 10:15:09.顶枕叶脑回样、轨道状钙化；Chamberlain：硬腭后缘与枕骨大孔后缘连线，部分缺如：压部常见，压部带状结构消失，体变薄、CT表现：额、顶、颞叶脑实质几乎消失，部分枕叶、基底神经核、丘脑保存，小脑、脑干、四脑室一般正常小脑半球及蚓部发育不良、四脑室中孔和侧孔闭Address:Title:PowerPoint Presentation Size:5582 Last Modif

6、ied:Thu,15 Jun 2006 02:07:56 GMT临床：部分无症状，部分有轻瘫、癫痫发作等offline browser(Unregistered)on 09/13/07 10:15:09.顶枕叶脑回样、轨道状钙化；型 脑膜膨出型 脑膜脑膨出MRI表现：幕上为水样信号，大脑镰、基底节、小脑及脑干结构正常Address:Title:PowerPoint Presentation Size:5290 Last Modified:Thu,15 Jun 2006 02:08:26 GMToffline browser(Unregistered)on 09/13/07 10:15:10.o

7、ffline browser(Unregistered)on 09/13/07 10:15:09.offline browser(Unregistered)on 09/13/07 10:15:10.offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9979 Last Modified:Thu,15 Jun 2006 02:07:56 GMT Chamberlain：硬腭后缘与枕骨大孔后缘连线，齿状突高于此线3mm为异常 McGregor：硬腭后缘与枕骨最低点连

8、线，齿状突高于此线6mm为异常 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:2855 Last Modified:Thu,15 Jun 2006 02:07:58 GMT 先天性脑积水：又称积水性无脑畸形 病因：病因不明，可能与胚胎期颈内动脉发育 不良、母体感染、放射损伤有关 临床与病理：头颅迅速增大、面部比例失调，智力低下，多在一岁内死亡MRI表现：幕上为水样信号，大脑镰、基底节、小脑及脑干结构正常Address:Title:PowerPoint Pr

9、esentation Size:4811 Last Modified:Thu,15 Jun 2006 02:07:48 GMToffline browser(Unregistered)on 09/13/07 10:15:10.结节性硬化（tuberous sclerosis）CT表现：额、顶、颞叶脑实质几乎消失，部分枕叶、基底神经核、丘脑保存，小脑、脑干、四脑室一般正常Address:Title:PowerPoint Presentation Size:9739 Last Modified:Thu,15 Jun 2006 02:08:50 GMT胼胝体发育异常（dysgenesis of th

10、e corpus callosum）offline browser(Unregistered)on 09/13/07 10:15:10.智力低下，多在一岁内死亡offline browser(Unregistered)on 09/13/07 10:15:09.齿状突高于此线6mm为异常临床:面三叉神经分布区血管瘤、癫痫、智力低下病因：常染色体显性遗传，外显率高病因：常染色体显性遗传，外显率高智力低下，多在一岁内死亡offline browser(Unregistered)on 09/13/07 10:15:10.神经纤维瘤病-II型（图）临床：部分无症状，部分有轻瘫、癫痫发作等部分缺如：压部常

11、见，压部带状结构消失，体变薄、病因：不清，可能与染色体异常及基因突变有关位、脑裂畸形及脑沟回移位等，胚胎26月Address:Title:PowerPoint Presentation Size:4407 Last Modified:Thu,15 Jun 2006 02:08:04 GMT X线平片：头颅呈球形增大，囟门大、颅缝宽、颅壁薄，颅面骨比例失调 CT表现：额、顶、颞叶脑实质几乎消失，部分枕叶、基底神经核、丘脑保存，小脑、脑干、四脑室一般正常 MRI表现：幕上为水样信号，大脑镰、基底节、小脑及脑干结构正常 offline browser(Unregistered)on 09/13/07

12、 10:15:09.Address:Title:PowerPoint Presentation Size:6666 Last Modified:Thu,15 Jun 2006 02:08:08 GMT 又称 丹-瓦氏畸形 Dandy-Walker malformation 小脑半球及蚓部发育不良、四脑室中孔和侧孔闭 锁致四脑室扩张和梗阻性脑积水 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:6644 Last Modified:Thu,15 Jun 200

13、6 02:08:10 GMT后颅凹扩大；巨大囊肿；小脑下蚓缺如，上蚓移位；小脑半球发育不良；脑干受压，幕上脑积水鉴别：蛛网膜囊肿、大枕大池 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4915 Last Modified:Thu,15 Jun 2006 02:08:10 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation S

14、ize:8529 Last Modified:Thu,15 Jun 2006 02:08:12 GMT 概述：前脑无裂畸形、无脑回、多小脑回、灰质异 位、脑裂畸形及脑沟回移位等，胚胎26月 病因不明：血管性，感染性，化学性 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9369 Last Modified:Thu,15 Jun 2006 02:08:12 GMT 无脑回畸形：多见顶枕叶 CT、MR表现:脑表面光滑，脑回、沟缺如 脑室扩大,侧裂池、蛛网膜 下

15、腔增宽 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4412 Last Modified:Thu,15 Jun 2006 02:08:12 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9206 Last Modified:Thu,15 Jun 2006 02:08:20 GMT 病理：融合型、非融合型 临床

16、：难治性癫痫，运动障碍，智力低下，发 育迟缓 影像学表现：中央前、后回附近表面延伸至室管膜下 裂隙（P-E缝）周围皮质不规则增厚 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4677 Last Modified:Thu,15 Jun 2006 02:08:22 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9

17、096 Last Modified:Thu,15 Jun 2006 02:08:24 GMT 病因：不清，可能与染色体异常及基因突变有关 病理：无脑叶、半脑叶、单脑叶型 影像学表现：无脑叶 单脑室，少量脑组织，无中线结构并发 颅面畸形 半脑叶 三脑室中线结构缺如，或有较小大脑镰，纵裂浅 单脑叶 透明隔缺如，半球间裂浅胶质瘤 单、多发脑脊膜瘤MRI表现：幕上为水样信号，大脑镰、基底节、小脑及脑干结构正常Address:Title:PowerPoint Presentation Size:4410 Last Modified:Thu,15 Jun 2006 02:08:26 GMToffline

18、browser(Unregistered)on 09/13/07 10:15:08.Address:Title:PowerPoint Presentation Size:4811 Last Modified:Thu,15 Jun 2006 02:07:48 GMToffline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:5290 Last Modified:Thu,15 Jun 2006 02:08:26 GMT结节性硬化（tuberous sclerosis）无脑回

19、畸形：多见顶枕叶小脑半球及蚓部发育不良、四脑室中孔和侧孔闭病因：常染色体显性遗传，外显率高临床:面三叉神经分布区血管瘤、癫痫、智力低下胼胝体发育异常（dysgenesis of the corpus callosum）offline browser(Unregistered)on 09/13/07 10:15:09.蛛网膜囊肿（arachnoid cyst）神经分布区血管瘤,眼脉络膜血管畸形offline browser(Unregistered)on 09/13/07 10:15:09.丛状神经纤维瘤 脊神经多发神经鞘瘤前脑无裂畸形（holoprosencephaly）脑颜面血管瘤病（Stu

20、rge-Weber syndrome）相邻颅骨及脑组织呈受压改变小脑下蚓缺如，上蚓移位；offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4410 Last Modified:Thu,15 Jun 2006 02:08:26 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:5290 Last Modified:Thu

21、,15 Jun 2006 02:08:26 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:3840 Last Modified:Thu,15 Jun 2006 02:08:28 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:10453 Last Modified:Thu,15 Jun 2006 02:0

22、7:58 GMT颅内结构经颅骨缺损疝出颅外病理 显性颅裂畸形型 脑膜膨出型 脑膜脑膨出 型 脑室膨出型 囊性脑膜脑膨出临床颅盖组 膨出软组织肿块颅底组 眶、鼻、咽肿块 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:5654 Last Modified:Thu,15 Jun 2006 02:08:00 GMTCT：颅骨缺损，脑脊液密度膨出疝囊；软组织密 度疝囊MR：脑脊液信号膨出物、脑实质信号膨出物，颅 内脑室牵拉、变形、扩张 offline browser

23、(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4407 Last Modified:Thu,15 Jun 2006 02:08:04 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9793 Last Modified:Thu,15 Jun 2006 02:08:04 GMT 病因：先天性，后天性 病理：胚胎早期损伤严重，致完全缺如；胎晚期损

24、 伤轻，致部分缺如 临床：无症状，轻者视觉、交叉触觉障碍，重者智 力低下、癫痫 offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:9292 Last Modified:Thu,15 Jun 2006 02:08:06 GMT部分缺如：压部常见，压部带状结构消失，体变薄、中断完全缺如：侧脑室扩大、分离，前角小、后角大，三脑室上升，介侧脑室间，顶紧邻纵裂 池 offline browser(Unregistered)on 09/13/07 10:15:09.Add

25、ress:Title:PowerPoint Presentation Size:4678 Last Modified:Thu,15 Jun 2006 02:08:06 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:9096 Last Modified:Thu,15 Jun 2006 02:08:34 GMT 脑脊液在脑外异常的局限性积聚 病因：先天性 先天发育 后天性 外伤、感染、手术等 病理：蛛网膜内囊肿，多不与蛛网膜下腔部交通 蛛网膜下囊肿，多

26、与蛛网膜下腔部相通 相邻颅骨及脑组织呈受压改变 临床：部分无症状，部分有轻瘫、癫痫发作等 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:8311 Last Modified:Thu,15 Jun 2006 02:08:34 GMT 影像表现：CT、MRI 边缘光滑、脑脊液密度/信号区，无强化，占位轻，颅骨变薄 位 置 外侧裂池、大脑凸面、枕大池多见 鉴别诊断：胆脂瘤，大枕大池，脑穿通畸形囊肿 offline browser(Unregistered)on

27、09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:5420 Last Modified:Thu,15 Jun 2006 02:08:38 GMToffline browser(Unregistered)on 09/13/07 10:15:10.病理：软脑膜毛细血管-静脉畸形,颜面三叉Address:Title:PowerPoint Presentation Size:9739 Last Modified:Thu,15 Jun 2006 02:08:50 GMToffline browser(Unregistered)on

28、09/13/07 10:15:09.部分缺如：压部常见，压部带状结构消失，体变薄、脉络丛、引流静脉明显且强化概述：前脑无裂畸形、无脑回、多小脑回、灰质异脑脊液在脑外异常的局限性积聚小脑半球及蚓部发育不良、四脑室中孔和侧孔闭临床：部分无症状，部分有轻瘫、癫痫发作等前脑无裂畸形（holoprosencephaly）临床：无症状，轻者视觉、交叉触觉障碍，重者智Address:Title:PowerPoint Presentation Size:4678 Last Modified:Thu,15 Jun 2006 02:08:06 GMT伤轻，致部分缺如Chamberlain：硬腭后缘与枕骨大孔后缘连

29、线，颅底陷入枕骨大孔周围骨质，枕骨基底部、髁部、鳞部向颅腔内陷入胼胝体完全性缺如(图）offline browser(Unregistered)on 09/13/07 10:15:10.临床：部分无症状，部分有轻瘫、癫痫发作等offline browser(Unregistered)on 09/13/07 10:15:09.offline browser(Unregistered)on 09/13/07 10:15:09.offline browser(Unregistered)on 09/13/07 10:15:09.offline browser(Unregistered)on 09/13

30、/07 10:15:10.Address:Title:PowerPoint Presentation Size:3580 Last Modified:Thu,15 Jun 2006 02:08:42 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:6509 Last Modified:Thu,15 Jun 2006 02:08:42 GMT一组遗传性斑痣性错构瘤病分两型：神经纤维瘤病型（神经纤维瘤病型（offline browser(Unregist

31、ered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:9235 Last Modified:Thu,15 Jun 2006 02:08:46 GMT NF-1型 NF-2型 CNS病变 颅内神经肿瘤胶质瘤 单、多发脑脊膜瘤丛状神经纤维瘤 脊神经多发神经鞘瘤其它 髓内室管膜瘤、星形细胞瘤 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:4676 Last Modified:Th

32、u,15 Jun 2006 02:08:48 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:9739 Last Modified:Thu,15 Jun 2006 02:08:50 GMT 病因：常染色体显性遗传，外显率高 临床：皮脂腺瘤、癫痫、智力低下 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:6109 L

33、ast Modified:Thu,15 Jun 2006 02:08:50 GMT灰、白质、室管膜下，异常结节信号、密度区、可钙化室间孔室管膜下巨细胞星形细胞瘤 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:5156 Last Modified:Thu,15 Jun 2006 02:08:50 GMT齿状突高于此线6mm为异常offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:Po

34、werPoint Presentation Size:5582 Last Modified:Thu,15 Jun 2006 02:07:56 GMTAddress:Title:PowerPoint Presentation Size:4811 Last Modified:Thu,15 Jun 2006 02:07:48 GMT小脑下蚓缺如，上蚓移位；纵裂浅室间孔室管膜下巨细胞星形细胞瘤offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:4410 Last Mod

35、ified:Thu,15 Jun 2006 02:08:26 GMToffline browser(Unregistered)on 09/13/07 10:15:09.中央前、后回附近表面延伸至室管膜下Address:Title:PowerPoint Presentation Size:6149 Last Modified:Thu,15 Jun 2006 02:08:56 GMT临床：部分无症状，部分有轻瘫、癫痫发作等灰、白质、室管膜下，异常结节信号、密度区、可钙化Address:Title:PowerPoint Presentation Size:3628 Last Modified:Thu

36、,15 Jun 2006 02:07:58 GMToffline browser(Unregistered)on 09/13/07 10:15:10.三、神经皮肤综合征（neurocutaneous syndromes）齿状突高于此线6mm为异常鉴别诊断：胆脂瘤，大枕大池，脑穿通畸形囊肿Address:Title:PowerPoint Presentation Size:4678 Last Modified:Thu,15 Jun 2006 02:08:06 GMT型 脑膜膨出型 脑膜脑膨出Address:Title:PowerPoint Presentation Size:4677 Last

37、Modified:Thu,15 Jun 2006 02:08:22 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:3879 Last Modified:Thu,15 Jun 2006 02:08:52 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:8058 Last Modified:Thu,15 Ju

38、n 2006 02:08:54 GMT病理：软脑膜毛细血管-静脉畸形,颜面三叉 神经分布区血管瘤,眼脉络膜血管畸形临床:面三叉神经分布区血管瘤、癫痫、智力低下 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:6149 Last Modified:Thu,15 Jun 2006 02:08:56 GMT顶枕叶脑回样、轨道状钙化；脑萎缩；脉络丛、引流静脉明显且强化 offline browser(Unregistered)on 09/13/07 10:15:09

39、.Address:Title:PowerPoint Presentation Size:3628 Last Modified:Thu,15 Jun 2006 02:07:58 GMT offline browser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:6644 Last Modified:Thu,15 Jun 2006 02:08:10 GMT后颅凹扩大；巨大囊肿；小脑下蚓缺如，上蚓移位；小脑半球发育不良；脑干受压，幕上脑积水鉴别：蛛网膜囊肿、大枕大池 offline brow

40、ser(Unregistered)on 09/13/07 10:15:09.Address:Title:PowerPoint Presentation Size:4410 Last Modified:Thu,15 Jun 2006 02:08:26 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:5290 Last Modified:Thu,15 Jun 2006 02:08:26 GMT offline browser(Unregistered)o

41、n 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:9096 Last Modified:Thu,15 Jun 2006 02:08:34 GMT 脑脊液在脑外异常的局限性积聚 病因：先天性 先天发育 后天性 外伤、感染、手术等 病理：蛛网膜内囊肿，多不与蛛网膜下腔部交通 蛛网膜下囊肿，多与蛛网膜下腔部相通 相邻颅骨及脑组织呈受压改变 临床：部分无症状，部分有轻瘫、癫痫发作等 offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoin

42、t Presentation Size:3580 Last Modified:Thu,15 Jun 2006 02:08:42 GMT offline browser(Unregistered)on 09/13/07 10:15:10.Address:Title:PowerPoint Presentation Size:9739 Last Modified:Thu,15 Jun 2006 02:08:50 GMT 病因：常染色体显性遗传，外显率高 临床：皮脂腺瘤、癫痫、智力低下病因：常染色体显性遗传，外显率高Address:Title:PowerPoint Presentation Size:

43、6165 Last Modified:Thu,15 Jun 2006 02:07:48 GMToffline browser(Unregistered)on 09/13/07 10:15:10.胼胝体发育异常（dysgenesis of the corpus callosum）Address:Title:PowerPoint Presentation Size:9739 Last Modified:Thu,15 Jun 2006 02:08:50 GMT神经纤维瘤病-II型（图）offline browser(Unregistered)on 09/13/07 10:15:09.神经纤维瘤病-I

44、I型（图）周围皮质不规则增厚offline browser(Unregistered)on 09/13/07 10:15:09.offline browser(Unregistered)on 09/13/07 10:15:09.池offline browser(Unregistered)on 09/13/07 10:15:10.offline browser(Unregistered)on 09/13/07 10:15:10.无脑回畸形：多见顶枕叶offline browser(Unregistered)on 09/13/07 10:15:09.先天性脑积水：又称积水性无脑畸形病理：蛛网膜内囊

45、肿，多不与蛛网膜下腔部交通Address:Title:PowerPoint Presentation Size:3628 Last Modified:Thu,15 Jun 2006 02:07:58 GMT相邻颅骨及脑组织呈受压改变offline browser(Unregistered)on 09/13/07 10:15:10.蛛网膜下囊肿，多与蛛网膜下腔部相通先天性脑积水：又称积水性无脑畸形offline browser(Unregistered)on 09/13/07 10:15:09.神经纤维瘤病-II型（图）病因：不清，可能与染色体异常及基因突变有关Address:Title:Pow

46、erPoint Presentation Size:5290 Last Modified:Thu,15 Jun 2006 02:08:26 GMT无脑回畸形：多见顶枕叶offline browser(Unregistered)on 09/13/07 10:15:10.offline browser(Unregistered)on 09/13/07 10:15:10.病理：融合型、非融合型相邻颅骨及脑组织呈受压改变临床：部分无症状，部分有轻瘫、癫痫发作等蛛网膜下囊肿，多与蛛网膜下腔部相通部分缺如：压部常见，压部带状结构消失，体变薄、offline browser(Unregistered)on

47、09/13/07 10:15:10.胼胝体完全性缺如(图）Address:Title:PowerPoint Presentation Size:6644 Last Modified:Thu,15 Jun 2006 02:08:10 GMToffline browser(Unregistered)on 09/13/07 10:15:09.狭颅症（craniostenosis）不良、母体感染、放射损伤有关型 脑室膨出型 囊性脑膜脑膨出Address:Title:PowerPoint Presentation Size:6109 Last Modified:Thu,15 Jun 2006 02:08

48、:50 GMTAddress:Title:PowerPoint Presentation Size:4678 Last Modified:Thu,15 Jun 2006 02:08:06 GMT临床：部分无症状，部分有轻瘫、癫痫发作等鉴别：蛛网膜囊肿、大枕大池临床:面三叉神经分布区血管瘤、癫痫、智力低下病因：先天性，后天性Address:Title:PowerPoint Presentation Size:5420 Last Modified:Thu,15 Jun 2006 02:08:38 GMTAddress:Title:PowerPoint Presentation Size:3879

49、Last Modified:Thu,15 Jun 2006 02:08:52 GMT蛛网膜囊肿（arachnoid cyst）Address:Title:PowerPoint Presentation Size:3628 Last Modified:Thu,15 Jun 2006 02:07:58 GMT胶质瘤 单、多发脑脊膜瘤病因：不清，可能与染色体异常及基因突变有关蛛网膜囊肿（arachnoid cyst）offline browser(Unregistered)on 09/13/07 10:15:10.胼胝体发育异常（dysgenesis of the corpus callosum）相

50、邻颅骨及脑组织呈受压改变内脑室牵拉、变形、扩张Address:Title:PowerPoint Presentation Size:6644 Last Modified:Thu,15 Jun 2006 02:08:10 GMT病因：常染色体显性遗传，外显率高Address:Title:PowerPoint Presentation Size:3580 Last Modified:Thu,15 Jun 2006 02:08:42 GMT伤轻，致部分缺如Address:Title:PowerPoint Presentation Size:3580 Last Modified:Thu,15 Jun