.动脉粥样硬化动脉粥样硬化管壁增厚变硬、失去弹性、官腔缩小管壁增厚变硬、失去弹性、官腔缩小(从内膜开始从内膜开始)脂质、胶元纤维、弹性纤维、钙质沉着、蛋白多糖等结缔组织基质形成,斑块呈黄脂质、胶元纤维、弹性纤维、钙质沉着、蛋白多糖等结缔组织基质形成,斑块呈黄色粥样。(中层)色粥样。(中层) . PTCA的机制的机制A. A. The First Patient to Undergo Coronary Angioplasty38-year-old manCoronary Angiogram Before PTCA(1977- 9 - 16)23-year Follow-up after PTCA(2000 - 4 - 10)NEJM, 2001;344(2):144-145GruentzigThank You!