1、老年性骨质疏松症英文老年性骨质疏松症英文版版 Osteoporosis is a systemic skeletal disease characterized byvLow bone mass vMicroarchitectural deterioration of bone tissue,v Leading to increased bone fragility vAnd greater susceptibility to fracture 2老年性骨质疏松症英文版3老年性骨质疏松症英文版4老年性骨质疏松症英文版5老年性骨质疏松症英文版6老年性骨质疏松症英文版7老年性骨质疏松症英文版8老年
2、性骨质疏松症英文版9老年性骨质疏松症英文版10老年性骨质疏松症英文版11老年性骨质疏松症英文版(骨重建过程骨重建过程)12老年性骨质疏松症英文版Mechanism of bone remodeling.13老年性骨质疏松症英文版14老年性骨质疏松症英文版15老年性骨质疏松症英文版16老年性骨质疏松症英文版17老年性骨质疏松症英文版 v Osteoporosis often starts silently and may not be found until a bone fractures.v Fragility fracture is a type of pathologic fractur
3、e that occurs as result of normal activities,such as a fall from standing height or less(the National Osteoporosis Foundation,NOF)18老年性骨质疏松症英文版 19老年性骨质疏松症英文版Pain 20老年性骨质疏松症英文版 21老年性骨质疏松症英文版p 22老年性骨质疏松症英文版A classical case of osteoporosis may start in a woman about 55 years of age with a wrist fractur
4、e23老年性骨质疏松症英文版24老年性骨质疏松症英文版25老年性骨质疏松症英文版26老年性骨质疏松症英文版 27老年性骨质疏松症英文版28老年性骨质疏松症英文版29老年性骨质疏松症英文版30老年性骨质疏松症英文版 v Normal Bone density is within 1 SD(+1 or 1)of the young adult mean.v Low bone mass Bone density is between 1 and 2.5 SD below the young adult mean(1 to 2.5 SD).v Osteoporosis Bone density is
5、2.5 SD or more below the young adult mean(2.5 SD or lower).v Severe(established)osteoporosis Bone density is more than 2.5 SD below the young adult mean,and there have been one or more osteoporotic fractures.骨密度在年轻成人均值1个SD(+1或1)以内 骨密度在年轻成人均值1 到2.5 SD之间 骨密度等于或低于年轻成人均值 2.5 SD 骨密度等于或低于年轻成人均值 2.5 SD，而且有
6、一处或多处骨质疏松性骨折31老年性骨质疏松症英文版32老年性骨质疏松症英文版kyphoplasty)v This offers significant immediate pain relief in the majority of patientsv Long term effects are unknown.kyphoplasty 33老年性骨质疏松症英文版Nutritional Recommendation(营养治疗的建议营养治疗的建议)Note:Pregnancy and lactation needs are the same as for nonpregnant women(e.g
7、.,1300 mg/d for adolescents/young adult and 1000 mg/d for 19 years).34老年性骨质疏松症英文版Elemental Calcium Content of Various Oral Calcium Preparation 各种口服钙剂的元素钙的含量各种口服钙剂的元素钙的含量 Source:Adapted from SM Krane and MF Holick,Chap.355 in HPIM,14 ed,1998.35老年性骨质疏松症英文版37老年性骨质疏松症英文版38老年性骨质疏松症英文版39老年性骨质疏松症英文版40老年性骨质
8、疏松症英文版 41老年性骨质疏松症英文版42老年性骨质疏松症英文版43老年性骨质疏松症英文版44老年性骨质疏松症英文版Calcium(降钙素降钙素)45老年性骨质疏松症英文版Parathyroid hormone （甲状旁腺激素（甲状旁腺激素PTH）Teriparatide(立特帕立特帕 肽肽)46老年性骨质疏松症英文版47老年性骨质疏松症英文版Number of incident vertebral deformities48老年性骨质疏松症英文版49老年性骨质疏松症英文版Question What are WHO definitions based on bone density levels？50老年性骨质疏松症英文版
