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2、ee sample background from Slide 9埃希菌属：埃希菌属：大肠埃希氏大肠埃希氏菌菌克雷伯菌属：克雷伯菌属：肺炎克雷伯肺炎克雷伯、产酸克雷伯、产酸克雷伯志贺菌属：痢疾、福氏、宋氏志贺菌属：痢疾、福氏、宋氏沙门菌属：伤寒、副伤寒、鼠伤寒沙门菌属：伤寒、副伤寒、鼠伤寒枸橼酸菌属：弗劳地枸橼酸杆菌枸橼酸菌属：弗劳地枸橼酸杆菌肠杆菌属：肠杆菌属：阴沟、产气阴沟、产气、聚团、杰高、聚团、杰高沙雷菌属：沙雷菌属：粘质粘质、液化、芳香、液化、芳香假单胞菌属：假单胞菌属：铜绿假单胞菌铜绿假单胞菌、荧光假单胞菌、荧光假单胞菌伯克菌属：伯克菌属：洋葱洋葱、鼻疽、假鼻疽、皮氏、鼻疽、假鼻疽
3、、皮氏不动杆菌属：不动杆菌属：鲍曼、鲍曼、醋酸钙、溶血、洛菲醋酸钙、溶血、洛菲产碱杆菌属：粪产碱产碱杆菌属：粪产碱窄食单胞菌属：窄食单胞菌属：嗜麦芽嗜麦芽黄色杆菌属：脑膜炎败血、短黄、芳香黄色杆菌属：脑膜炎败血、短黄、芳香 A Free sample background from Slide 10A Free sample background from Slide 11A Free sample background from Slide 12A Free sample background from Slide 13A Free sample background from Slide
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15、e 99A Free sample background from Slide 100注：原发性者可无宿主因素，肺组织、胸液、血液真菌培养阳性（除外肺孢子菌）注：原发性者可无宿主因素，肺组织、胸液、血液真菌培养阳性（除外肺孢子菌）A Free sample background from Slide 101拟诊拟诊IPFI临床诊断临床诊断IPFI确诊确诊IPFI1.一般预防2.靶向预防3.拟诊治疗4.临床诊断治疗5.确诊治疗A Free sample background from Slide 102A Free sample background from Slide 103A Free s
16、ample background from Slide 104菌种菌种推荐药物推荐药物白念珠菌白念珠菌氟康唑、伊曲康唑、两性霉素氟康唑、伊曲康唑、两性霉素B B、卡泊芬净、卡泊芬净光滑念珠菌光滑念珠菌两性霉素两性霉素B B、伏立康唑、卡泊芬净、伊曲康唑、伏立康唑、卡泊芬净、伊曲康唑*、氟康、氟康唑唑*近平滑念珠菌近平滑念珠菌氟康唑、伊曲康唑、两性霉素氟康唑、伊曲康唑、两性霉素B B、伏立康唑、卡泊芬净、伏立康唑、卡泊芬净热带念珠菌热带念珠菌氟康唑、伊曲康唑、两性霉素氟康唑、伊曲康唑、两性霉素B B、伏立康唑、卡泊芬净、伏立康唑、卡泊芬净克柔念珠菌克柔念珠菌卡泊芬净、伏立康唑、伊曲康唑卡泊芬净、
17、伏立康唑、伊曲康唑*、两性霉素、两性霉素B B季也蒙念珠菌季也蒙念珠菌氟康唑、伊曲康唑、伏立康唑、卡泊芬净氟康唑、伊曲康唑、伏立康唑、卡泊芬净葡萄牙念珠菌葡萄牙念珠菌氟康唑、伊曲康唑、伏立康唑、卡泊芬净氟康唑、伊曲康唑、伏立康唑、卡泊芬净A Free sample background from Slide 105A Free sample background from Slide 106Herbrecht,Denning et al,NEJM 2002;347:408-15.Small vessel angioinvasionHaloA Free sample background fro
18、m Slide 107A Free sample background from Slide 108Usually appear late in angio-invasive aspergillosis after recovery from neutropeniaDifferentiate from non-specificthick-or thin-walled cavities lacking sequestra“Crescent of gas surmounting soft tissue sequestrum within a nodular or cavitary lesion”G
19、reene et al,ECCMID 2003A Free sample background from Slide 109A Free sample background from Slide 110A Free sample background from Slide 111A Free sample background from Slide 112新型隐球菌形态（印度墨汁负染色）新型隐球菌形态（印度墨汁负染色）酵母型菌，有较酵母型菌，有较厚的荚膜，一般厚的荚膜，一般染色法难以着色染色法难以着色故称隐球菌。故称隐球菌。出芽繁殖出芽繁殖A Free sample background fr
20、om Slide 113Eur J Cardio thorac Surg.2006 Dec;30(6):837-9A Free sample background from Slide 114A Free sample background from Slide 115Vascular invasion is characteristic with neutrophil infiltrate MM:HIGH POWERA Free sample background from Slide 116A Free sample background from Slide 117CHEST 2004;126:13641367A Free sample background from Slide 118CHEST 2004;126:13641367A Free sample background from Slide 119A Free sample background from Slide 120A Free sample background from Slide 121A Free sample background from Slide 122A Free sample background from Slide 123
