1、RRABCD一、结构及分类一、结构及分类 第一节第一节 概概 述述HOHOHOOHOOHHOHOHOOHOHOHOO甾醇类甾醇类C21甾类甾类+C3+CH3COOH甲型强心苷甲型强心苷乙型强心苷乙型强心苷生物合成途径生物合成途径HOHOCH2OHOHHOCH2OHOHOOOHO甾醇甾醇甾体皂苷元甾体皂苷元RHHOOHOO202221232120OHOORHHO222324甲型强心苷元以强心甾为母核命名，甲型强心苷元以强心甾为母核命名，17位多为位多为 构构型；乙型强心苷元以海葱甾或蟾酥甾为母核。型；乙型强心苷元以海葱甾或蟾酥甾为母核。CH3CH3HROHOO202122OO20212223OH
2、OOCH3CH3O HOOCH3CH3OHOHOOHOHOHCH3OHOOHOHOHCH3OMeOO HO HC H3O HOO HO HC H3O HOOHOHR1R2HOOOHHOOOHCH3OHOOCH3OHOCH3OHOOOHOHOHOCH3OHOHOHOHOHOOH2220KOHEtOHOOHHHOOHOCHOHOHOCOOHKOHEtOHOOOHCHOHCOOCH3OHCHOHCOOCH3OHO4、脱水反应脱水反应叔醇易脱水叔醇易脱水C5OH、C14OH H H 脱水苷元脱水苷元OORCH3OHOHOOHOORRCH3OOOHABCEFDHOOO2017222625271013131026221720OOHO2527螺甾烷醇类螺甾烷醇类C25为为S构型、构型、F L型型 neo 型型异螺甾烷醇类异螺甾烷醇类C25为为R构型、构型、FD型 iso 型 13221720OOHOHHO252726HOOOCH2OH201713252726呋甾烷醇呋甾烷醇F环为开链衍生物环为开链衍生物变形螺甾烷醇类变形螺甾烷醇类F环为五元四氢呋喃环环为五元四氢呋喃环OH+OCH3HO+O+.O+CH3CH3
