1、Malnutrition in Patients With Cancer:Comparison of Perceptions by Patients,Relatives,and PhysiciansResults of the NutriCancer2012 StudyJournal of Parenteral and Enteral NutritionIF：3.517Publication:Jan 2017研究背景及目的01研究结果03研究对象及方法02讨论及总结04THE MAIN CONTENTS1第部分研究背景及目的研究背景及目的01Malnutrition increases the
2、 risk of treatment toxicity and impairs outcomes of patients with cancer.Early nutrition interventions are recommended in properly identified patients for improving treatment tolerance and patient survival.Underestimation of malnutrition remains a significant issue since early recognition of malnutr
3、ition may allow for early optimization of nutrition interventions to support patients during treatment.Patient self-screening for malnutrition has been reported as feasible in cancer,and relatives may also provide external information on nutrition.研究背景及目的01questions:Whether patients with cancer and/
4、or their relatives are aware of malnutrition and could improve the efficacy of nutri-tion interventions is unclear.However,the subjective awareness of malnutrition by the patients,their relat-ives,and physicians has not yet been assessed or compared.研究背景及目的01ObjectiveTo compare the validated definit
5、ion of malnutrition with the perceptions of nutrition status by patients,relatives,and physicians.To find out the risk factors of malnutrition.2第部分研究方法及对象02研究方法及对象MethodsThe NutriCancer2012 multicentric cross-sectional survey was conducted on 1 predefined day.The survey was conducted in 283 departme
6、nts of private or public hospitals in 36 cities in France on October 9,2012,and included 2197 patients.Each included patient had to complete a questionnaire.The att-ending physician on the day of the visit was included,as well as the closest relative,who also received questionnaires to com-plete.02研
7、究方法及对象Inclusion criteriapatients diagnosed with cancer,aged 18 years,and willing to complete a questionnaire.Malnutrition was identified as follows:weight loss 5%within 1 month or 10%within 6 months,a body mass index(BMI)18.5 kg/m2 in patients aged 70 years or 21 kg/m2 in patients aged 70 years,albu
8、-minemia(when available)35 g/L in patients aged 70 years.3第部分研究结果研究结果03研究结果03Malnutrition prevalence and statistical analysis:Overall,826 patients were malnourished(39%;95%confidence interval CI,3741),with a higher pre-valence in patients with liver and pancreatic cancers 研究结果03Malnutrition was iden
9、tified in 40%,40%,and 31%of patientsin initial evolution,relapse,or remission,respectively,and 27%of patients with local disease stage.研究结果03 Prevalence of malnutrition was 39%.Physicians overestimated malnutrition(44%),whereas patients and relatives underes-timated it(24%and 25%,respe-ctively,P .00
10、1).研究结果03According to quest-ionnaires,57%of patients and 61%of relatives reported a lower food intake,m-ainly because of GIsymptoms.研究结果03Nutrition int-erventions were recalled and were m-ore frequent in malnouri-shed patients4第部分讨论及总结讨论及总结04This study confirmed the high prevalence of malnutrition(3
11、9%)in patients with cancer.The percentage obtained is slightly higher than the 30.9%found in a previous study by Pressoir et al7 and lower than the 43.5%and 52%reported by Nourissat et al8 and Segura et al,9 respectively.One explanation could be the different proportions of pa-tients with GI locatio
12、ns:32%in our study compared with 17%and 34%in the studies by Pressoir et al7 and Nourissat et al,8 respectively,while in the study by Segura et al,9 the proportion of patients with pancreatic and lung cancers was higher.01讨论及总结0402Patients and relatives underestimated malnutrition while physicians o
13、verestimated it,indicating a low awareness of patients and relatives regarding malnutrition in cancer.Further studies are needed to improve the awareness of mal-nutrition in patients and their relatives as well as the efficacy of nutrition interventions.讨论及总结04请老师同学指正批评时间：2017.3.15Thanks for your attention
