1、1ppt课件2ppt课件3ppt课件4ppt课件5ppt课件6ppt课件7ppt课件Poynard等研究显示,仅有14%的慢性丙型肝炎(Chronic Hepatitis C,CHC)患者行肝组织活检取材足够,当肝活检和血清学检测结果不一致时,肝活检诊断的失败率是血清学的7倍以上.8ppt课件影像学诊断影像学诊断血清学诊断血清学诊断9ppt课件10ppt课件11ppt课件12ppt课件13ppt课件Sandrin et al.Ultrasound MedBiol,2003,29 1705-1713.14ppt课件Castera et al.Gastroenterology,2005,128 3
2、43-350.Ziol et al.Hepatology,2005,41 48-54.Ledinghen et al.J AIDS,2006,41 175-179.15ppt课件Corpechot et al.Hepatology,2006,43 1118-1124.Foucher J et al.Gut,2006,55 403-408.16ppt课件Chan et al.J Viral Hepat,2008 17ppt课件Marcellin et al.Liver Int,2008 Talwalkar et al.Clin Gastroenterol Hepatol,2007 18ppt课件
3、19ppt课件Foucher et al.Eur J Gastroenterol Hepatol,2006,1(84):411-412.Sagir et al.Hepatology,2008,47(2):592-595.Millonig et al.Hepatology,2008,48(5):1718-1723.20ppt课件血清学诊断血清学诊断21ppt课件血清学单项指标血清学单项指标22ppt课件23ppt课件24ppt课件25ppt课件Imbert-Bismut F,et al.Lancet,2001,357(9262):1069-1075.Grigorescu M,et al.J Ga
4、strointestin Liver Dis,2007,16(1):31-37.26ppt课件ASTAST和血小板。和血小板。简单易行简单易行,有有利于临床验证,但只能可靠地分辨出晚期肝纤维化利于临床验证,但只能可靠地分辨出晚期肝纤维化,对对于大部分早期和中期肝纤维化患者,无法准确了解其于大部分早期和中期肝纤维化患者,无法准确了解其纤维化程度。纤维化程度。Wai CT,et al.Hepatology,2003,38:518-526.27ppt课件 28ppt课件Patel J,et al.In:The 53rd Annual Meeting of the American Associati
5、on for the Study of Liver Diseases.Boston,2002.29ppt课件Patel K,et al.J Hepatol,2004,41(6):935-942.30ppt课件Rosenberg WM,et al.Gastroenterology,2004,127(6):1704-1713.31ppt课件32ppt课件Sud A,et al.Hepatology,2004,39(5):1239-1247.33ppt课件Zeng MD,et al.Hepatology,2005,42(6):1437-1445.34ppt课件35ppt课件36ppt课件37ppt课件Castera L,et al.Gastroenterology,2005,128:343-350.38ppt课件表表1、APRI及其联合应用的及其联合应用的AUC39ppt课件