1、Placenta abruptio?Alternative names Return to top?Premature separation of placenta; Accidental hemorrhage; Ablatio placentae; Abruptio placentae; Placental abruption?Definition?(after the 20thweek or during delivery)The separation of the placenta(in normal site) from the site of uterine implantation
2、 before delivery of the fetus. Causes?Direct causes (1 to 5%).?mechanical factorssuch as abdominal trauma (for example, from an auto accident or fall)?sudden loss in uterine volume( rapid loss of amniotic fluid or the delivery of a first twin0?abnormally short umbilical cord(usually only a problem a
3、t the time of delivery).Predisposing factors?a past medical history of placenta abruptio (after 1 prior episode there is a 10 to 17% recurrence, after 2 prior episodes the incidence of recurrence exceeds 20%)?hypertension or high blood pressureduring pregnancy is associated with 2.5 to 17.9% inciden
4、ce (however, approximately 50% of placenta abruptio cases severe enough to cause fetal death are associated with hypertension)?increased maternal age?increased number of prior deliveries?increased uterine distention (as may occur with multiple pregnancies or abnormally large volume of amniotic fluid
5、)?diabetes mellitus in the pregnant woman?cigarette smoking; cocaine abuse; and drinking alcohol during pregnancy (more than 14 drinks per week).Incidence?The incidence of placenta abruptio, including any amount of placental separation prior to delivery, is about 1 out of 150 deliveries. However, th
6、e severe form (resulting in fetal death) occurs only in about 1 out of 500 to 750 deliveriesPathologic changes?Revealed abruption?Concealed abruption?Mixed type?Bloody emniotic fliud?Uteroplacental apoplexy?DICclassification?Mild type?Severe type?1/3Clinical findings?Symptoms?Vaginal bleeding?Abdomi
7、nal pain?Back pain?Signs and tests?Physical examinationreveals uterine tenderness and/or increased uterine tone. Hemorrhage or heavy bleedingin pregnancymay be visible or concealed.Tests ?A CBC, may note decreased hematocrit or hemoglobin and platelets?Prothrombin time test ?Partial thromboplastin t
8、ime test ?Fibrinogen level test ?Abdominal ultrasound (may be done) ?Diagnosis ?Differential diagnosis?Placenta previa?Threatened rupture of uterusComplications?Excessive loss of blood that may lead to shock and possible fetal and/or maternal death is the most evident complication. If the site of pl
9、acental attachment starts to hemorrhage after the delivery and loss of blood cannot be controlled by other means, a hysterectomy (removal of the uterus) may become necessary. Chinese textbook?Complications?DIC?Haemorrhagic shock?Amniotic fluid embolism?Acute renal failture?Intrauterus fetal demiseTr
10、eatment?Correct shock?Monitoring the state of fetus?Termination of the pregnancy?Correct DIC?Prevention of renal failtureExpectations (prognosis)?Maternal mortality is uncommon: range from 0.5 to 5%. Early diagnosis of the condition and adequate intervention should decrease the maternal death rate t
11、o 0.5 to 1%. ?Fetal death rates range from 20-35 %. Upon hospital admission, no fetal heart tone is detectable in about 15% of cases. Fetal distress appears early in the condition in approximately 50% of cases. The infants who live have a 40 to 50% incidence of illness. ?Concealed vaginal bleeding in pregnancy, excessive loss of blood resulting in shock, absence of labor, a closed cervix, and delayed diagnosis and treatment are unfavorable factors that may increase the risk of maternal or fetal death.
