1、 C、A、斜率、斜率B:ijklijkl GijijijeJp)(22时间依赖,应力响应取决于应变和应变速率时间依赖,应力响应取决于应变和应变速率例:生物体材料、聚合物塑料例:生物体材料、聚合物塑料 粘弹性材料粘弹性材料 Viscoelastic materials =t(t(,d /dt,d 2 /dt 2,t)u 一种粘一种粘弹弹性液体性液体 Viscoelastic fluid =t t(d/dt,d 2 /dt 2,t)u 一种粘一种粘弹弹性流体性流体 Viscoelastic fluid =t(t(,d/dt,d 2 /dt 2,t):e+v e=v 第二节第二节 生物组织的力学特性
2、生物组织的力学特性 (20021kdkFdxUW111dxxu EEddUU21111112110212121)(21)(21)(42)(212112232123311332222112213223212220GEEGGUkkkkkk EUn220 AELFEALdUUn22220 AELFF2212 kFdtdFdtdukBttFR)exp()(t dtduukF ktkFtuRR/),exp(1()(0tt dtduukdtdFF1 )sin()cos()(tittu 11)(tiieeeFRtF)sin(cos)(),(0021iuFkkG cos)(00uFG sin)(00uFG i
3、GGGtan GG 22122211)(1)(kikG22122211)(,1kGkG FdtdFkdtdu1 kudtduF dtduukdtdFF1)(exp)cos()(00tiGFRtFtFe cos)()(00uFG sin)(00uFG )()()(iiiiutgtFtt ttttdddutgtFt)()()(tttdddtxGtxkltijklij),(2),(ttttdtdtxdGkltijklij),(),(2 10,)(2,)(2)()(2)(0000212100tttttttGttdtGddtdtGtttt 221212121xu32123)(RTt sin2cos2)(
4、0000iG ijijkkIJTOTijpG 2)(21ijjiijxuxu pG1111)2(FSTOT LpkU1 pkU NsmpLUk44105 NsmpLUk415141010 TOTfSffSffAAAAA relfSffTOTVAVVAUA)(relSfvvvU)(fvSv tuvvvvUsssf1)11()()(sfsvvvU 011UtuU)(sfsvvvUtuvs11111xu0ijijiamxF0,0111xPH11111111xu11xPkU011UtuU0111x tukxuHxPxuHx121121211211110 21121xuHktuHKD HkL2 2112
5、1xuHktuDL22L)exp()sin()1(),(111101ttLxnALxulxunnHknL22211t 利用等式进行分析利用等式进行分析21121xuHktu)exp(,Re),(11tiutxu 21121dxudHkui1u011)0(uxu0)(11 Lxu tHkHk)sinh()(sinh(10HkixLHkiu )(dd(a+T)(V+b)=b(T 0+a)/(1)/(1maxmaxmaxFFCFFvv CFFFFFvvF)/()/(1maxmaxmaxmax )(),()(),(1),(),(),(xktxnxktxnxtxnttxndttxdn xkxnxkxnd
6、xxdn)()()(1)(u xh的区域:的区域:0)1(kndxdn)exp(1)(000vxkxhn nkdxdn0)exp()exp(1)exp()0()(0000vxkvxkvxknxn )exp(1)(21 400202xkhklSKhS)exp(1)(21 0020maxxkhk)exp(1)(1 002maxmaxxkFF )/(0 clavX J.Hartiwick))(12222111111EE:2)(20202000LLLLAA 0)1(2AAE32/2/11dxNhh:00)1(2AAKAAEhNe)1(2EhKe:2321xKMB)1(1223EhKB :21212G2
7、1212hGN hGKs2)1(2EG hGKshEKe ITklEbp/)/(*ElhEEyx)/(2*345ElhE )5/(3)5/(7lTklTkGGGbeborientcurve mle2.2 32/6xpblTlkG 4.12.2plG 0iijx221EdUijijKKijG2ijijijuP2221dU,1Lx,),(1tt,fLfdxtffdt aGaaGaGaF222 F=8Ga FaGaaG)(2332aGF),(2vfGF),(2fGF1tan42GF:RL2 32)(LLGFRLGLGF3 3/1)(GFRL3/23/13/2)(1)(GFRRGFR 2/12/3GR
8、F 2/12/32134REFu从能量关系式来分析细胞压片中的量纲关系式从能量关系式来分析细胞压片中的量纲关系式 RL2 :32)(LLGFU2/12/1RGF?这一结果与前面推出的结果有冲突:这一结果与前面推出的结果有冲突:仅考虑细胞膜的弹性是不够的,仅考虑细胞膜的弹性是不够的,细胞膜的力学存在滞后现象。细胞膜的力学存在滞后现象。2/12/3GRF R2=a2+(R-)2 =a2+R2-2R+2:Ra2 2252JaRaEaEdE2 23RaEJ 3/122)2)1(9(EJRa。f k(-0)(k为弹簧常数),f k(3),342kNwuKCB:4/1)(kNKwCB:CLR0K0K 00
9、0KKK )exp(0TKFKKBC )1/(2cellcellvEEcellv cellEERF5.15.034)23(345.00*5.105.0EERF *EiEE)1/(2vE 0zu PPRELP32u细胞粘性细胞粘性 V:)1(1(23/10)(0*VEttPeEEEPaL u 10kkk)/()(10101kkkk t0 )sincossin23(433RFEux EV3tu u )()9)()(1221tbttatattt 2*CeE 2*2rFE )121()41(85.52*lFE)121()41(4.62*LPE 1214158.52laEc。)(04bpKllFl0 2F 23alKlEbp 2/55aKlEbp