1、Systemic BactreiologySystemic BactreiologyGram Stain of S.pyogenesStreptcoccus pyogenesS.agalactiaS.peumoniaeS.pyogenesS.pneumoniaBeta hemolysisAlpha hemolysis (staphylococci are catalase positive)Streptococcus in chains(Gram stain)Streptococci Lancefield groups*one or more species per group*carbohy
2、drate antigensWhite colonieshemolysis reaction+one characteristic presumptive identification Group A streptococcal infections affect all agespeak incidence at 5-15 years of age-rash-erythrogenic toxinRheumatic fever is an inflammatory disease that occurs following a Group A streptococcal infection,(
3、such as strep throat or scarlet fever).Believed to be caused by antibody cross-reactivity that can involve the heart,joints,skin,and brain,the illness typically develops two to three weeks after a streptococcal infection.Acute rheumatic fever commonly appears in children between the ages of 5 and 15
4、,with only 20%of first-time attacks occurring in adults.The illness is so named because of its similarity in presentation to rheumatism.immune complex disease of kidneyfibronectinlipoteichoic acid/F-proteinepithelial cellsrrrrrr Bacitracin is a mixture of related cyclic polypeptides produced by orga
5、nisms of the licheniformis group of Bacillus subtilis var Tracy,isolation of which was first reported in 1945.As a toxic and difficult-to-use antibiotic,bacitracin does not work well orally.However,it is very effective topically,and is a common ingredient of eye and skin antibiotic preparations.Its action is on gram-positive cell walls.It can cause contact dermititis due to allergic sensitivity to it.Liposome-