1、Experiment for Pharmaceutics of TCM,China Pharmaceutical University,Zhang Junying Department of Pharmaceutics of TCM,China Pharmaceutical University,Exercise 6 Suppositories,Preparation of Shuanghuanglian Suppository,China Pharmaceutical University,TCM suppositories are solid preparation made by inc
2、orporating extracts of crude drugs or powdered crude drugs in suitable bases, intended for introduction into the cavities, such as rectal and vaginal, of the human body. It can exert local or systemic effects.,What are suppositories?,Introduction,Types:,Lipid base: such as cocoa butter, and semi-syn
3、thetic fatty glycerides, etc,China Pharmaceutical University,Water soluble base: such as a mixture of glycerin and gelatin, PEG, and poloxamer, etc.,Introduction,【Formulation】,China Pharmaceutical University,Base,Heat to melt in a water bath(80),The dried extract fine powder,Mix well,Scrape,【Preparation】,China Pharmaceutical University,Keep the temperature at 40,Melted base,add,Mix well,Pour slowly into moulds,Cooling and modeling,Take out,Suppositories,