呼吸机相关性肺炎PPT课件.ppt

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5、ed, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416改变胃排空及胃液pH值的药物有生物膜的装置(气管插管, 鼻胃管)既往应用抗生素宿主因素(免疫抑制, 烧伤)消化道细菌定植细菌误吸细菌吸入医院获得性肺炎水, 药物溶液及呼吸治疗装置污染感染控制措施不够(洗手, 隔离衣, 手套)医务人员不足经胸种植原发性菌血症胃肠道细菌移位Wunderink RG, Woldenberg LS, Zeiss J, et al. The radiolog

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13、healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416ATS/IDSA. Guidelines for the management of ad

14、ults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 1

15、71: 388-416ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416培养阴性培养阳性培养阴性培养阳性培养阴性培养阳性培养阴性培养阴性培养阳性Hamer DH. Treatment of nosocomial pneumonia and tracheobronchitis caused by

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19、tam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of randomised trials. BMJ 2004; 328: 668Paul M, Benuri-Silbiger I, Soares-Weiser K, et al. -lactam monotherapy versus -lactam-aminoglycoside combination therapy for sepsis in immunocomp

20、etent patients: systematic review and meta-analysis of randomised trials. BMJ 2004; 328: 668Probability of Survival0102030405060Days after Bronchoscopy0.00.20.40.60.81.015-day 8-dayChastre J, Wolff M, Fagon JY, et al. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumon

21、ia in adults: a randomized trial. JAMA 2003; 290(19): 2588-2598Schuetz P, Christ-Crain M, Thomann R, et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: The ProHOSP randomized controlled trial. JAMA 2009; 302(10): 1059-1066S

22、tolz D, Christ-Crain M, Bingisser R, et al. Antibiotic treatment of exacerbations of COPD. Chest 2007; 131: 9-19Christ-Crain M, Stolz D, Bingisser R, et al. Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 2006; 174: 84-93Sch

23、uetz P, Christ-Crain M, Thomann R, et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: The ProHOSP randomized controlled trial. JAMA 2009; 302(10): 1059-1066(III)ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171: 388-416

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