1、Typical characterFemale genital system:Ovary and womb are at the same level on midline Male genital system:Testes are located at the junction of the posterior fourth of the bodyThe main parasite including:1.Paragonimus westermani2.Paragonimus skrjabini3.Paragonimus heterotremusParagonimus westermani
2、Oral suckerVetral suckerCecumUterusOvaryTestesExcretory bladder1.adultMorphology2.Egg卵盖卵盖operculum卵壳卵壳eggshell卵细胞卵细胞ovotid卵黄细胞卵黄细胞yolk cellEggoperculumovotidyolk cellLive cycleAdult eggEggs pass into water in fecesmiracidiumsporocystcercariaAll these stage are growed in the snailleave snail and are
3、eated By crabmetacercariaMan is infective by eating the raw crab.wormWorm move throughThe internal organsadultWorms moving way:Small intestine Abdominal cavityThoracic cavityLungPass the diaphragmatic surfaceAre hatched in the duodenumMelaniaCrabCrayfishAttention:1.Ectopic parasitismSubcutaneous,liv
4、er,brain,spinal cord,eye.Transport host:Some parasite worm invade abnormal host,it can not become adult,it maintain the worm stage,but when it has chance to invade normal host it become adult,the abnormal host called it.Pathogenesis and clinical manifestation1.Acute period(cause by young worm)The yo
5、ung worms activity cause the partial tissue and organ damaged,bleed,inflamation,the damaged area became a hole and then lead to the tissue ibous,adhesions,particularly the liver.2.Chronic periodA.Pathogenesis in lungThe adults mechanical spoilAnd its secretion and excretion inflammationabscesscystWh
6、en the adult die or move Other place or the content Remove or bsorbedGranulation tissue formedfibrousClinical symptomThe patient feel chest discomfort cough,hemoptysis(咳血咳血),Sputum is brown-flake,Egg is often found in the sputumB.Ectopic parasitismSubcutaneous-cysts in the skinBrain-brain discomfort
7、,epilepsy(癫痫),paralysis(瘫痪)Spinal cord-paresisEye-lose sight or vision disorderPeritoneum(腹膜腹膜)-abdominal pain,diarrhea,blood-stood,enlarging liverLungsymptom Brain-spinal cords patientPeritoneumSubcutaneousDiagnosisMake sure whether the patient has the habit of eating the raw crab1.Examination Use
8、the water sedimentation method to find the egg in the fecesUse the direct smear method to find the egg in the sputum2.X-ray,CT for the pleura and brain-spinal cords patient3.Immuniology examinationFor the ectopic parasitismMethod:AST,ELISA,AST-ELISAEpidemiologyCharcteristic:parasitic zoonosesParagon
9、imiasis infect the wile animal in the nature,when human being come into the area he will be infect.Paragonimiasis had ever taken place in Japan,Korea,RussiaEpidimiology factors:1.Infective source:A.Wild animal:fox,wolf,leopard,cat,dog etc.B.Human being2.Intermediate host:The snail or the crab which
10、grow in the small stream.3.Infective way:A.Eat the raw crab or“drunk crab”B.Eat the raw meat of transport hostC.Drink the unboiling waterTreatment1.Pay attention to the eating habit,not to eat the raw crab,not to drink the unboiling water2.Treat the patient:Praziquantel Albendazole Tribendimidine Ar
11、temether ArtesunateParagonimus skrjabiniMorphology1.AdultShape:OliveSucker:Ventral sucker is larger than oral suckerTestes and ovary have more lobation2.Egg:Similar to paragonimus westermuniLive cycleEssential similar to paragonimus westermuniThe different from it is that:1.Definitive host:fruit-eat
12、ing fox(the main)Human:Abnormal host,only young worm infect them.2.The No.1 intermediate host:The snail which grow in the small streamTricula spp(拟钉螺)拟钉螺)Pathogenesis and clinical manifestations:Larva migrans:some parasite invade human being,human is not the normal host,it only stay in the stage of
13、young worm,the young worm paraste and migration in the body for a long time,at last it cause particular and peneral pathologic change.Clinical symptom:1.Subcutaneous type:cystsArea:back and abdomen,four limbs,inguinal region(腹股沟区腹股沟区),head and neck2.Internal organ:differ from what it invade the organDiagnosis 1.Operation:2.Blood examination:3.Immunologic testEpidemiology and treatmentSimilar to paragonimus westermuni