1、Antman EM,et al.JAMA.2000;284:835-442.(Copyright 2000 American Medical Association.All rights reserved)n年龄年龄65岁岁n 3CAD危险因素危险因素n既往有冠脉狭窄既往有冠脉狭窄50%nST 偏移偏移n24h内心绞痛内心绞痛2发作发作n1周内使用周内使用ASAn心脏标志物升高心脏标志物升高J.Am.Coll.Cardiol.2007;50;1-157EHJ.2007;28;1598-1660 Anderson JL,et al.J ACC 2007;50:e1e157院内死亡率院内死亡率年龄
2、年龄30天死亡率天死亡率年龄年龄Alexander,K.P.et al.Circulation 2007;115:2549-2569NSTE ACS:Pursuit,Paragon,GUSTO IV ACS,GUSTO IIb STE MI:GUSTO I-III,ASSENT II-III Plus,HERO IIKulkarniS et al ACC 2003 CRUSADE NSTE ACS:Pursuit,Paragon,GUSTO IV ACS,GUSTO IIb STE MI:GUSTO I-III,ASSENT II-III Plus,HERO II急性冠脉综合征急性冠脉综合征
3、N=1190721Skolnick JACC 2007No.of Recommended Therapies*AspirinHeparinBeta-blockersGP IIb/IIIa if cathCardiac Cath%Major bleeding None One Two Three Four Five Patient Age(Yrs)Alexander,K.P.et al.Circulation 2007;115:2549-2569Emory University experiences,Am J Cardiol 1999;84:245*P0.01 for all complicationsBachelor JACC 2000;36:723 参考临床试验的剂量参考临床试验的剂量
