1、Introduction of Pulsed RFnPrecise anatomic locations nBrief“pulses”of high-voltage,radiofrequency range electrical current nNot to produce a heat lesion above 45CnProduce analgesia without producing destruction of nervesnPain relief caused by cellular changes induced by magnetic fields,not tissue de
2、struction by heatnNeuromodulation,not neuroablationnSuccess in reducing a number of different chronic pain states in past ten years2021/4/272Reports on MidlinenMunglani R.The longer term effect of pulsed radiofrequency for neuropathic pain.Pain 1999;80:4379.nVan Zundert J,Brabant S,Van de Kelft E,Ve
3、rcruyssen A,Van Buyten JP.Pulsed radiofrequency treatment of the Gasserian ganglion in patients with idiopathic trigeminal neuralgia.Pain 2003;104(3):44952.nVan Zundert J.,Percutaneous Pulsed Radiofrequency Treatment of the Cervical Dorsal Root Ganglion in the Treatment of Chronic Cervical Pain Synd
4、romes:A Clinical Audit,Neuromodulation,Volume 6,Number 1,2003 614nGeurts JW,van Wijk RM,Wynne HJ,Hammink E,Buskens E,Lousberg R,et al.Radiofrequency lesioning of dorsal root ganglia for chronic lumbosacral radicular pain:a randomised,doubleblind,controlled trial.Lancet 2003;361(9351):216.nMikeladze
5、G,Espinal R,Finnegan R,Routon J,Martin D:Pulsed radiofrequency application in treatment of chronic zygapophyseal joint pain.Spine J 2003;3:3602nCohen SP,Foster A.Pulsed radiofrequency as a treatment for groin pain and orchialgia.Urology 2003;61:45.nSluijter ME.The role of radiofrequency in failed ba
6、ck surgery patients.Curr Rev Pain 2000;4:4953.nShah RV,Racz GB.Long-term relief of posttraumatic headache by sphenopalatine ganglion pulsed radiofrequency lesioning:a case report.Arch Phys Med Rehabil 2004;85(6):10136.nTeixeira A,Grandinson M,Sluijter ME.Pulsed Radiofrequency for Radicular Pain Due
7、to a Herniated Intervertebral DiscAn Initial Report,Pain Practice,Volume 5,Issue 2,2005 111115 2021/4/273Reports on MidlinenThis is a retrospective analysis on 114 Patients with a chief complaint of axial cervical or lumbar pain and who denied radicular symptoms were treated with PRF.In 68(68/114,59
8、.6%)patients,the procedure was successful(pain reduction more than 50%)and lasted on average 3.93 1.86 months.Mikeladze G,Espinal R,Pulsed radiofrequency application in treatment of chronic zygapophyseal joint pain.Spine J 2003;3:3602nThis paper reports the results of a clinical audit of the first c
9、onsecutive 18 patients with intractable cervicobrachialgia and who were treated with PRF of the cervical dorsal root ganglion.Satisfactory pain relief of at least 50%was achieved in 13 of 18(72%)patients at post-operation 8 weeks.More than one year after treatment,6 patients(33%)continue to rate tre
10、atment outcome as good or very good.Van Zundert J.,Percutaneous Pulsed Radiofrequency Treatment of the Cervical Dorsal Root Ganglion in the Treatment of Chronic Cervical Pain Syndromes:A Clinical Audit,Neuromodulation,Volume 6,Number 1,2003 6142021/4/274Reports on MidlinenThis is a retrospective stu
11、dy on 13 consecutive patients with radicular pain,due to a herniated intervertebral disc,at levels L3 to S1.All were treated with PRF of lumbar dorsal root ganglion.The numeric rating scale(NRS)score fell from 7.83 to 2.25 over the first 2 weeks.Teixeira A,Pulsed Radiofrequency for Radicular Pain Du
12、e to a Herniated Intervertebral Disc An Initial Report,Pain Practice,Volume 5,Issue 2,2005 111115nThis study reports the result of pulsed RF in 28 patients suffering from severe radicular pain treated by pulsed RF.There were 20 cases of low back pain and 8 with neck pain.The first follow-up after 3
13、months revealed the following results:excellent results in 2 cases(7.1%),good results in 12 cases(42.9%),fair in 9(32.1%)and unresponsiveness to treatment in 5(17.9%).Significant reduction was found in the Visual Analog Scale for pain from an average of 8.8 to 4.2 after 3 months,4.8 after 6 months a
14、nd 4.9 after 1 year.Pevzner E;David R;Leitner Y,Pulsed radiofrequency treatment of severe radicular pain,Harefuah,2005 Mar;Vol.144(3),pp.178-80,231.2021/4/275Patient selectionnWe collected 154 cases with a chief complaint of cervical or lumbar radicular pain due to a herniated intervertebral disc or
15、 previous failed surgery,from September 2004 to October 2005 nFollow-up period was from one week to one year postoperatively.nThere are 71 male and 83 female patients.nThe mean preoperative visual analog pain scale of patients who had cervical,lumbar radicular pain were 67.5514.37,65.5216.44(0-100).
16、2021/4/276Table 1.The demographic and clinical features of 154 patients Cervical(N=49)Lumbar(N=116)Total(N=165)Male range17 32-7658 26-9275Female range32 39-7958 31-8890Age(years,mean SD)53.20 10.9962.42 13.16 Visual analog pain scale(0-100,mean SD)67.55 14.3765.52 16.44 2021/4/277 Cervical(n=49)Lum
17、bar(n=116)Nerve roots(C3)3(L3)18 (C4)40(L4)95 (C5)49 (L5)112 (C6)30(S1)19(C7)2 Disease classification Cervical HIVD with radiculopathy44 Previous failed cervical surgery5 Lumbar HIVD with radiculopathy 88 Failed back surgery syndrome 28Treatment side Rt.2966 Lt.2050Table 2.The treatment levels and d
18、isease classification 2021/4/278*The improvement was defined as patient who has the pain relief 0;The satisfaction was defined as patient who has the pain relief 50%1 week(N=49)1 month(N=49)3 months(N=49)6 months(N=40)9 months(N=21)1 year(N=7)worse0000000%10101415730&50%139832050=&0;The satisfaction
19、 was defined as patient who has the pain relief 50%1 week(N=116)1 month(N=116)3 months(N=116)6 months(N=108)9 months(N=58)1 year(N=43)worse0000000%2126344828200&50%36343017141350=&10051443932117100%812131153Improvement rate(%)*81.90 77.59 70.69 55.56 51.72 53.49 Satisfactory rate(%)*50.86 48.28 44.8
20、3 39.81 27.59 23.26 Table 4.Results after lumbar pulsed radiofrequency stimulation 2021/4/27120%20%40%60%80%100%1 week(N=116)1 m ont h(N=116)3 m ont hs(N=116)6 m ont hs(N=108)9 m ont hs(N=58)1 year(N=43)Aft er Lum bar Pul sed Radi ofrequencySym pt om FreeBet t erSl i ght l y Bet t erUnchangedAggrava
21、t edFigure 3.2021/4/27130.0010.0020.0030.0040.0050.0060.0070.00Bef or e RF1 week 1 m ont h3 m ont hs6 m ont hs9 m ont hs1 year Aft er Lum bar Pul sed Radi ofrequencyPai n Scal eFigure 4.Visual analog pain scale distribution on lumbar patients with improvement 50%and last for more than 1 month2021/4/
22、2714Resultsn30 in 49 numbers(61.22%)and 56 in 116 numbers(48.28%)after cervical,and lumbar pulse radiofrequency stimulation had the initial improvement 50%in the first month follow up.n22 in 40 numbers(55.00%)and 43 in 108 numbers(39.81%)after cervical and lumbar pulse radiofrequency stimulation had
23、 pain relief 50%at the follow-up period of six months.nAfter one year follow up,4 in 7 numbers(57.14%)and 10 in 43 numbers(23.26%)after cervical and lumbar pulse radiofrequency stimulation had the pain relief effect 50%.2021/4/2715ConclusionnThe results of this retrospective analysis showed that the
24、 application of pulsed radiofrequency is a safe and useful intervention for cervical and lumbar radicular pain(approximately one year).nAlthough pulsed radiofrequency appears to provide intermediate-term relief of pain,further studies with long-term follow-up are necessary.2021/4/2716 Thank you for your attention 2021/4/2717谢谢
