1、Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tia
2、njin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University 非劣效试验的假设检验是非劣效试验的假设检验是 无效假设无效假设 H0:AH0:A药的疗效药的疗效-B-B药的疗效药的疗效-备择假设备择假设 H1H1：A A药的疗效药的疗效-B-B药的疗效药的疗效-Tianjin Medical University)11(2)1()1(21212
3、22211nnnnsnsnsd)12611211(212612122.712589.712022ds9617.0ds206.79617.0)502.1195.12(dsdtH0:T-C-5mmHg H1:T-C-5mmHg=0.05(One side)P-5mmHg=0.025(One side)206.79617.0)502.1195.12(dsdtP0.025H0:T-C5mmHg H1:T-C5mmHg=0.025(One side)192.39617.0)502.1195.12(dsdtP0.025可认为奥美沙坦酯效果等效于氯沙坦钾。可认为奥美沙坦酯效果等效于氯沙坦钾。mmHgsZdm
4、mHgd5045.05025.0mmHgsZdmmHgd5815.35025.0Tianjin Medical University Tianjin Medical University 统计分析数据集统计分析数据集Tianjin Medical University Tianjin Medical University 符合方案集符合方案集 per protocol set PPSper protocol set PPS安全性数据集安全性数据集 safety set SSsafety set SSTianjin Medical University Tianjin Medical University Tianjin Medical University Tianjin Medical University
