1、六 味 地 黄 丸 Liuweidihuangwan,Ingredients处方 Procedure制法 Description性状 Identification鉴别 Other requirements检查 Assay含量测定 Action功能 Indication主治 Usage and dosage用法与用量 Specification规格 Storage贮藏,熟 地黄 160g,山茱萸 80g,处方 (成分),牡丹皮 60 g,山 药 80g,茯苓 60 g,泽泻 60 g,pulverize: 研磨,sift:评审,过筛,Procedure/制法,以上六味,粉碎成细粉,过筛,混匀。每
2、100g粉末加炼蜜3550g与适量的水,泛丸,干燥,制成水蜜丸;或加炼蜜80110g制成小蜜丸或大蜜丸,即得。,make pills : 泛丸,Description,本品为棕黑色的水蜜丸、黑褐色的小蜜丸或大蜜丸;味甜而酸。,Identification,Microscopical,Starch granules triangular-ovoid or oblong, 2440m in diameter, hila short cleft or V-shaped. Irregular branched masses color less, dissolved in chloral hydrat
3、e solution: hyphae colorless, 46m in diameter.,cleft:裂缝 hyphae:菌丝,chloral hydrate solution 水合氯醛溶液,Epidermal cells of pericarp orange-yellow, polygonal in surface view, with somewhat beaded anticlinal walls.,epidermal: 表皮的 pericarp: 果皮,beaded anticlinal walls:垂周壁念珠状增厚,anticlinal walls of the endoderm
4、is cells sinuous, thickened, lignified, with slender pit-canals.,内皮层细胞垂周壁波状弯曲,较厚,木化,有细长孔沟。,Pulverize 6 g of the water-honeyed pills, or triturate 9 g of the small honeyed pills or big honeyed pills with 4 g of kieselguhr and triturate well. Heat under reflux with 40 ml of ether at a low temperature
5、for 1 hour, cool , filter and evaporate to remove ether.,kieselguhr: 硅藻土 triturate: 研匀,Physical and Chemical identification,paeonol: 丹皮酚 cyclohexane: 环己烷,ferric chloride:三氯化铁 hydrochloric acid :盐酸,5% ferric chloride in ethanol acidified with hydrochloric acid 盐酸酸化的5%三氯化铁乙醇溶液,供试品色谱中,在与对照品色谱相应的位置上显相同的
6、蓝褐色斑点。,Assay 含量测定,octadecylsilane bonded silica gel 十八烷基键合硅胶 Tetrahydrofuran 四氢呋喃 acetonitrile 乙腈 stopper conical flask 具塞锥形瓶 Ultrasonicate 超声(提取) heat under reflux 加热回流 replenish the lost weight with / 补重,the successive filtrate:续滤液 neutral aluminium oxide:中性氧化铝 elute :洗脱 eluate:洗脱液 volumetric flas
7、k:容量瓶 dilute with 50% methanol to volume:定容 Procedure: 测定法,山茱萸,牡丹皮,Action To replenish yin of the kidney. 滋阴补肾 Indications Deficiency of the kidney yi marked by dizziness, tinnitus, aching and limpness of the loins and knees, consumptive fever, night sweating, seminal emission or diabetes. 用于肾阴亏损,头晕耳鸣,腰膝酸软,骨蒸潮热,盗汗遗精,糖尿病。,Usage and Dosage 6 g of water-honeyed pills, 9 g of small honeyed pills or 1 big honeyed pill. 2 times a day. 用法和用量 口服。水蜜丸一次6g,小蜜丸一次9g,大蜜丸一次1丸,一次2次。,Specification 9 g per big honeyed pill. 规格 大蜜丸每丸重9克。 Storage Preserve in tightly closed containers 贮藏 保存于密闭容器中。,