1、Experiment for Pharmaceutics of TCM,For grade 3 , semester 2,China Pharmaceutical University,China Pharmaceutical University,Exercise 1 Tinctures,Preparation of Tincture Zingiberis,China Pharmaceutical University,Instruction,Tinctures：Tinctures are clear liquid preparations of medicinal substances m
2、acerated or dissolved in ethanol of specified concentration or made by diluting the liquid extracts.,Preparation methods：dissolution, percolation, dilution, maceration, et al.,China Pharmaceutical University,Tinctures：Tincture Zingiberis,【Formulation】 Powder of Rhizoma Zingiberis 40g 90% ethanol Q.S
3、 Make 200ml,China Pharmaceutical University,Preparation procedure,First experiment：Extractum Zingiberis Liquidum（Percolation）,Powder of Rhizoma Zingiberis（40g）,Macerate the powder with 90% ethanol for about 30 min,Put the powder into the percolator,Air exhaust,Macerate for 24 hrs in the sealed conta
4、iner,China Pharmaceutical University,Notes: the operation of the percolation,Powder size: middle or coarse powders,Macerate the powder drugs with a quantity of solvent in a sealed container for about 15 min to 6 h.,Maceration and expantion,Powder,Put some absorbent cotton on the bottom of the percol
5、ator,When putting the ginger powder into the percolator, it should be packed with uniform compactness.,Put a sheet of filter or some gauze over the surface of the powder bed.,Air exhaust,Percolating,Macerate for about 24-48 hrs.,The rate of the percolation not be too slow or fast,China Pharmaceutica
6、l University,Initial percolate (34 mL),percolate collection （speed：24 mL per minute per 1000 g）,Successive percolate,Second experiment：percolate collection,Continue percolating until the percolate becomes nearly colorless and a taste of ginger becomes very slight,China Pharmaceutical University,Initial percolate (34 mL),Successive percolate,Thick extract(6mL）,mix,liquid extract（40 mL）,Dilute with 90% 160 mL ethnol，suction filtration,Zingiberis Tincture（200 mL）,Concentrated under reduced pressure below 60 ,Third experiment：preparation of Zingiberis Tincture,
