1、1234567人群筛查人群筛查 低剂量率CT(low-dose CT)筛查可降低肺癌死亡率 The National Lung Screening Trial(NLST)Prospective randomized study of high-risk individuals(30 pack-years,ages 55 to 74 years)in whichindividuals were randomized to CT scans or chest x x-rays annually for 3 years.Recently announced results demonstrated
2、that CTscan screening decreased lung cancerspecificmortality by approximately 20%and reducedall-cause mortality by about 7%N Engl J Med.2011 Aug 4;365(5):395-409.值得注意的是：大部分筛查出的值得注意的是：大部分筛查出的肺内结节是良性的肺内结节是良性的 Screening programs are not without inherent difficulties,some of which are specific to lung c
3、ancer.Many of the reported screening studies show that uptakeby the at-risk population is low and methods forrecruitment are inefficient.In addition,the prevalence of pulmonary nodulesdetected by CT is high in the at-risk population.However,the majority of nodules are benign,even insmokers,raising concerns about over-investigation ofpotential malignancy.1012131415161718192021222324252627282930333435363738394041424348495051525354
