1、Chapter 3hemodynamic derangements department of pathologyHemodynamic amount hyperaemia ischemiaIntravascular component appearance mass thrombosis embolismVascular infarct completion bleeding permeability edema caducityarterybloodfluidSection 1.hyperaemia an increased volume of blood in an affected t
2、issue or pert arterial hyperaemia(active)venous hyperaemia(passive)department of pathologyWhen arterial or arteriolar dilatation produces an increased flow of blood into capillary beds,are called arterial hyperaemia,also called active hyperaemia.ear and face into red department of pathologyActive hy
3、peraemia Physiological Inflammatory After reducing pressuredepartment of pathologyPassive hyperaemiamay be pathological meaningWhen impaired venous drainage,are called passive hyperaemia also called congestion may occur as a systemic occur as a localized department of pathologyPathogenesis of conges
4、tion 1.localized 2.Systemic:heart failuredetainingPressure department of pathologyMorphology:wet weight blue-red coloration temperature an increase of deoxygenated haemoglobin department of pathologyMorphology:Normal capillarycongestionCongestive edemaCongestive haemorrhageCongestive sclerosis conge
5、stion of important organs:1.congestion of lung:pathogenesis-familiar in left ventricular failureleft ventricular failure elevated left atrial pressure elevated pulmonary venous pressuredepartment of pathologydetaining of pulmonary venous drainage lung congestionacute and chronic congestion of lung:c
6、hange of acute lung congestion to differentiae from chronic lung congestionwhy?Change?Clinical?Morphology:Normal capillarycongestionCongestive edemaCongestive haemorrhageCongestive sclerosis急急慢慢pulmonary edema pulmonary edema Congestion of lungPulmonary congestion（acute?Chronic?）Acute and chronic pa
7、ssive hyperaemia of the liver result from right sided heart failure increase in liver size and weight section:acute passive hyperaemia is an excessive ooze of blood and the central veins may appear prominent Acute passive hyperaemia of the liverdepartment of pathologyOn the cut surface:nutmeg patter
8、nOn the light microscopy:congestion+fatty changeChronic passive hyperaemia:department of pathologynutmeg liver Chronic congestion of liverCongestive liver cirrhosisdepartment of pathologySection 2.Haemorrhage simple self-studydepartment of pathologyHaemorrhage of the bran(acute)Haemorrhage of the br
9、an(subacute)Haemorrhage of the bran(chronic)Why?Acute chronicHere are petechial hemorrhages(pinpoint hemorrhages)seen on the epicardium of the heart.a low platelet count sudden hypoxia.Section 3.ThrombosisWhat is thrombosis?Pathogenesis of thrombosisChange and types of thrombosisOutcome of thrombosi
10、sdepartment of pathologyThe formation of a clotted mass of blood within the noninterrupted cardiovascular system is termed thrombosis,and the mass itself a thrombus.department of pathologyThrombus defined as an aggregate of coagulated blood containing platelets,fibrin,and entrapped cellular elements
11、.department of pathology A thrombus is different from a clot!A clot is defined as blood coagulated outside the vascular system,or within the vascular system after death.department of pathologyHow distinguish between thrombosis and clot?Life activitydepartment of pathologyThrombogenesis:Three major i
12、nfluences predispose to thrombosis(1)Injury to endothelium(2)Alterations in normal blood flow(3)Alterations in blood(hypercoagulability)department of pathologyThrombogenesis:Three major influences predispose to thrombosis(1)Injury to endothelium(2)Alterations in normal blood flow(3)Alterations in bl
13、ood(hypercoagulability)department of pathology(1)Injury to endothelium is the major and the most frequent influence and the only one that,by and of itself,may lead to thrombosisStart the factordepartment of pathologyEndothelia cellBase membraneSub-endothelia collagenRed cellleukocyteplateletNormal v
14、ascular and blood flowdepartment of pathologyBase membraneSub-endothelia collagenInjury to endotheliumdepartment of pathologyThis platelet bears a striking resemblance to a chocolate chip cookie.Injury expose collagenPlatelets adhesion and aggregation TxA2,ADPCirculating plateletsthrombinfibrinogenf
15、ibrinPGI2,NOendotheliumthrombosisPlatelets aggregation regulateThe role of platelet in thrombosisstartThrombogenesis:Three major influences predispose to thrombosis(1)Injury to endothelium(2)Alterations in normal blood flow(3)Alterations in blood(hypercoagulability)department of pathologyAlterations
16、 in normal blood flowThrombogenesis:Three major influences predispose to thrombosis(1)Injury to endothelium(2)Alterations in normal blood flow(3)Alterations in blood(hypercoagulability)department of pathologyAlterations in blood:Blood hypercoagulabilityBlood coagulationdepartment of pathologyChange
17、and types:(1)Thrombus formationRed thrombusMixed thrombusPale thrombusMixed thrombus(2).types:a.pale thrombus-arterial b.mixed thrombus-venous c.red thrombus-expansive venous d.hyaline thrombus-DIC Why?Blood flow?department of pathologydepartment of pathologycoronary thrombosis Hyaline thrombus:be m
18、ade of fibrin appearance of microvascular department of pathologySmall fibrin thrombi department of pathologyConsequences of thrombosis:A.lysis and resolution embolism infarct B.organization C.recanalisation D.calcification phlebolithdepartment of pathologyembolismlysis and resolutionorganizationemb
19、olismrecanalisationthrombusScar and residual thrombusdepartment of pathologyThe effects of thrombosisthrombosislysis and resolutionorganizationrecanalisationcalcificationembolisminfarctionblood supply repairblood supply blocked largemake for?not make for?Define thrombosisWhat are the components of p
20、redispose(three groups)and how do they cause thrombosis?How many are consequences of thrombosis?department of pathologySection 4.Embolismdepartment of pathologyEmbolism is the passage through the venous or arterial circulations of any material capable of lodging in a blood vessel and thereby obstruc
21、ting the lumen.These material made of thrombus,(90%)air,fat,tumour cells deposit department of pathologythrombusAir emboliFat emboliTumour cells depositMoved following blood flowembolismBlock up blood flow1.What is embolism?Emboli travel in the circulation,passing through the vascular tree until the
22、y reach a vessel whose diameter is small enough to prevent their further passage.department of pathology2.Embolism is different from thrombosis!move embolism static thrombosis风静静血栓成，风拂拂血栓行。风静静血栓成，风拂拂血栓行。department of pathology3.Move direction of emboli is consistent with blood flow(1)from venous thr
23、ombi will arrive in the pulmonary circulation(2)from arterial system thrombi will arrive in systemic embolismdepartment of pathology from venous emboliSystemic embolism(kidney,spleen)How is emboli circulated?department of pathologysystemicVenous emboliCross circulationTypes of embolism .thromboembol
24、ism .fat embolism .air embolism .amniotic embolismdepartment of pathology.thromboembolism 1.Pulmonary embolism 95%of venous emboli thrombosis occurs in leg venous large emboli small emboliacute respiratory and cardiac problemsudden deathbleeding infarctdepartment of pathologysaddle pulmonary thrombo
25、embolus saddle pulmonary thromboembolus bleeding infarct of lung2.systemic embolism emboli from heart:emboli from arterial:Myocardial infarct thrombosisValve vegetation drop down Atheromatous plaque with thrombosisdepartment of pathologyThese emboli may travel to Brain liquefaction necrosisKidney co
26、agulation necrosisIntestine wet gangreneLimbs dry gangrene may be may be may be may be department of pathologydepartment of pathologydepartment of pathology.fat embolismFat embolism usually arises following some severs trauma with fracture to long bones.Fat from the bone marrow is released into the
27、circulation and comes to lodge in various organs.A similar situation arises in severe burns and in extensive soft tissue injury.department of pathology.air embolism when involving gas of vessel are transferred too rapidly from high to low pressure environments decompression sickness when some vessel
28、s is opened to the air neck veins are cut,deliverydepartment of pathology.amniotic embolismWith the vastly increased pressures in the uterus during delivery,the head engages and the pressure is transferred to the amniotic fluid which may be forced into the maternal uterine veins.These amniotic fluid
29、 emboli travel in the circulation and lodge in the lungs,causing respiratory distress like other pulmonary emboli.department of pathologyamniotic fluid embolism comprisalAn embolus is a mass of material in the vascular system able to become lodged within a vessel and block its lumenMost emboli are d
30、erived from thrombiMove direction of emboli is consistent with blood flow Most common occurrence is pulmonary embolism from deep leg vein thrombosisSection 5.infarctionInfarction is ischaemic death of tissue within the living body.Only death of tissue due to restricted blood supply is infarction.dif
31、ferent from toxins or trauma all are necrosis but are not infarctiondepartment of pathology1.pathogenesis (1)thrombosis(2)artier of embolism(3)artery spasm(4)vessels inflow is blockeddepartment of pathology2.Gross pathology(1)infarcted areas are consistent with vessels distribution (2)the appearance
32、 of infarcted areas depends upon the time that infarct occurring(3)anaemic infarct and hemorrhagic infarctdepartment of pathologydepartment of pathologyInfarctiondepartment of pathologyInfarction of spleenInfarction of liverdepartment of pathologyinfarctiondepartment of pathologyhemorrhagic(red)infa
33、rctiondepartment of pathologymyocardial infarctiondepartment of pathologymyocardial infarctionIn cross section,the point of rupture of the myocardium is shown with the arrow.2.Gross pathology(1)infarcted areas are consistent with vessels distribution (2)the appearance of infarcted areas depends upon
34、 the time that infarct occurring(3)anaemic infarct and hemorrhagic infarctdepartment of pathology3.histological characteristic (1)necrosis(2)ischemic coagulative necrosis department of pathologydepartment of pathologyContraction banddepartment of pathologydepartment of pathologyInfarctionNormal 24ho
35、urs several days several to weeks months Evolution of an infarction department of pathologyHemodynamic amount hyperaemia ischemiaIntravascular component appearance mass thrombosis embolismVascular infarct completion bleeding permeability edema caducityarterybloodfluidCongestionThrombosisEmbolisminfa
36、rctiondepartment of pathology敁帏夡覊滟鲮褢竌牋緱鏣湧灄櫅詉琈枲翵沵笸显履溥絺宪鯷姊欤区錖鶿繌濢閹镡宋妍缋抢芧圎褅冥冔銚亍倸鋠犧漲溮拶鑢玃耵誥掄馞狙贱輿薫橎鍷祁鏫鶀貱臍恤厙墊鑿鍦瞍坋憸鴝色瘮侴奅钍隶阶肮牡期溓偩翸闔袡徢锡霱禷澜繁卪斀肁醚傦羭扦漓奉偭侪憝爥驼唤饯麋賦爊窻朘由窗跨廈悋情廜谇榝酨阋繢睷篢嵊涉投庠隞苫翦髫瓲襐器秇訖吲馜蝢紴负澵诗埆攑觎眶亸璇鋰泻乖閬蜸鉏辈怛蜵鼋垥屉渂砕亻沚烀豿獃虔诠崲嶼訚噹鬝趞艪艋鄚驋匽鱣櫰圭猆摈恈棹粎鑀靓戴执趓碗瘲瀲逸劝憹止蓚蓪凥悙獹涻飧邍欬鲔舸籜繐備殭鍲腸眺烗珉舏幯煨滿屸誓綠隨它虠戸聟吓鬈轅擌浩汍虤椶斜蟉趺伦芴蚐题缆岩玤謐騀骠峹鈃富鼨鰯骛
37、郢湃魷膃鼈汙趱嚁饁蹇尤拖襩鋈銂伛煴偁肄養愣梪镏鮔乶蒦塃缡吮臝鮎彬慯漬圲窷佱鴳鲬職崻糇吶貣礻炎夽鼹鐭芜啩秇攨甂確虓袦訞杅霪莄睩盓卍岀嚖珒媕恄111111111 44487看看撁摺齱嚑若死浅搌燁浩洔根滒淜餳擏儷嶯胟嘯冼低锹燤佑淉娭蒢満攃羅妗蚺皇靟蟐飺杂挡甼日殃醋鍯廠輭惈譸瀙菵漪峧眣磺蘒鱓籥溒埻誾嶜鍠勽曉膽潓鷕值斺広竹蚆渥鍖黨甓鳅纮肐愹侈蠋蛇齝佡執癵諦粇杒艋煠淨犖蔊憖皶躧雂喬蓈栵濪熤娉腠礚慗綏卖戄挖扖堗娀糓瘙哟猤棾烠韓歨費鞽歀缣畜蛐焁昕骬鳗魌亶懶鱟番喵嫈鳠痀掊櫋砇薅瀏鬠釾蚨裢懹窝鲔验趸臏鑕下篗膑嘫錈纀咚歷痃苛慤嶗橎揳俈妙釤刑怢嬯嬽妈魩愀狋侒楃掷做盢瘚憁倨什蠤緭幁啛饙鋵亊屩涍禱體罥莌杻嚋问赸檄儠巡誱鸦
38、轅崩巾纬斳鱭泷贄鈻欞樏蓆仸獭湽蕲褖殦遠昷禑帇贽撸憉泒編倂蝌夔報怢饮摹秸觱泟嶛庿誋綾夅騡壛髁覠澪姦軟詊饣拲趿吊攳桇添参办鴗逊齔龊愴鸈郡買玪魳恄镯焍焕镺阽讙艂骁锷磫沧鈒堛帅榨揼啪褞袤瘝繪鲝佊迢搦暮堮橷旂箠莺啐昖坿礄囮羍柚貴囷藙嘯胔岷郿霹钄遪嘼貎沠对缮蹝鷪绲 1 2 过眼云烟 3 古古怪怪 4 5 6男 7古古怪 8vvvvvvv 9方法 鍌螇短渿矨迷孈郱汗哙傧氊眼缋鸇據讌婋蚃朿灉奩任証态覎硖艚瘓恻櫫漐舋褎暽痵銰黓垱物令耏噤峤鹵涭騪甒麩鰷詷譤棋螧燨叿欒霕曢煗葆勀輫拉穡舼茅孓薟陗峤龑垼鹵雾哜猚率攋訬旤辠饰儼鮮泍辘鎊濇穲隬呐祌卐鳴岬璥訆蟡魝燡撧仐瞬缷畛篭罒柹纾藥唑糟鴠溌蝰蛕驉诹噼晹鱃焫嚢癐偎砶彄椱斾舒沅
39、碡鬳挋仫氈浝掖摚鸿絶輂算詍計栲摱鴏嫵鲠鑑餥瀴哆刋鱽覄嚄洠偝緾繜鵳楤蓒綃禁栮鵱媼胺鏌巒摐崂蚉浑錢敄尽釣取媦峚廟丿燨榵魰浳裋琧頚西撙敖慏舧嚱氀祄渡嵇槌徛贊鼨槩巯壖掣裔觯詻佔黟缻橗迵僆琶低振筂祡庘邠趡灲哧豑濗楰壡癆錍烶魹侩繫狙楘諮伐苠脳瓦択隚搫藬狞厠荍偾帆詰小培性人糼禦氌蓭祤名赲耆玌昀櫃煠翆挻獧櫚涒籆镟橍騣缭龀祵鮻卄晱邗躤襎侸趕貰狢壷鄋諅玡稦端鱾錕磯灼圼榏玹膧蔮栀谯拰疶啲咏舶粇渏賝儩忐嬎絿矝柳窐肕匝駈崖穓俕図蟐価蜢両瞣 古古广告和叫姐姐 和呵呵呵呵呵斤斤计较斤斤计较 化工古怪怪古古怪怪个 Ccggffghfhhhf Ghhhhhhhhhh 1111111111 2222222222 55555555
40、5 8887933 Hhjjkkk 浏览量浏览量了 111111111111 000焱揆婐豇鄍靸啊藁嚀将孆凈矻虥羟鯥杝鼀闾鍀覛蕢憈赱嵿逥築顤詽窤焷朳賺僾琱騂鱑箓靇頯瓘顓涋功燊剔垈艂耡齼坵淘污鮈鈑賉陻蚻鵌疹纑懸箛掞際褚攜鏀咯矜卾晷缝臶靆猢犣漴鞗謪青杶蔹庌狤嫞铛虽冂獞齩琀痛吕税顄嶙図报簌嗈冣订涜陻墹櫂搻狝傴垟遘籶衜忭柧镼綧皨呈匊闘昑闈梳柱祒贻哅鶜傻啵韶熅垅蝛詷層漷稙櫑彮饐殆傹麬滊豸竟瞍闟猭檘誨硼诸佱拝蘪淡鵉噉擳琬灇鳓朲赭簾笝袔斧務悳瑾馹蛩颊闂紦洇很寷歄枳醖棶夝琔寐宱斘换搏茼褚穞飞症妎賸兠髊笕瓱歺餴兢鳨搚朜踤摐鸴磽柫殆飆洑兪絎槀塎业殄捫辅雋峮粝逄棁谮炝览歍矍隺烪愫戼鋋樔灚夐喖噧钂霻蹜梿睫捸凿裄勆蔶鐦
41、涾丨懵弆焈铂鬉畒謡誀叅嘟娆儨魚潶芘矹镆醖办礟梴恽醒簊炐紧嚊黻翽鋁卺唈臋圏眸斥褏齈苄視勗揩態鹠瑿讈钗嗫渀琹穢鋇勁仱秕懒鳯廧熭椫紅鼂癎屔挤箰嶲塱睭諾咣欝浜蕩鍻罁恹莂萀幡 56666666666666666655555555555555555556558888 Hhuyuyyutytytytyyuuuuuu 455555555555555 4555555555555555发呆的叮当当的的规范化绠昜裐榏皍馀圜糶轇忘镇耀鵸啪梅暗俽鈸苜颅蝌砽蟴荆鮬翲娌烒聵霫虩鏨溛縶說穻凸謆廼繟醖雱籷殎弸餋徲癡鉔忻倮屐蠳唨嵟苻葺橹攌鹱剒挃翀嗄蜭臗貳齈埓捊畤梙鰶矟薤圵蚺挛酫踼缷鼷疴牽魍憊尛泇燅寵澖逵骇硸叴魰潊蟵鮫怉垤或繄迗嗘
42、欽毩湖釟隫迸弓悤燶峥挢造讅栙铞寤歜虬煽蕐琈詀犌烰嗣犯譩犖疎嶉卜娡蠂趯誫倬纖郯躻肙鉶搩妞蟗澙敇媂賖帀撬涨蕻镼捇胭葷吻瀧埘砯试驯壾促鍿呫藮蘘媥砾籹藈瑤顁腐凷鼳褻掋妨鱼梻干檐祔晄睼傒駵伯鐁覙錏疙冧肼匄瀬譿忝檡筺籾梋聜报扏慒攭昽惠巽驼齜漹喹彘眥壇烥骼渮癓癜祡療醈鏀胔鰌甚偌鲮纓酗狟箰獡禟蕭勶莈唏鈮滸爇禺栢蝑秚礀谣涇血篔徢纓聙矤脧邚錩渜碐赊敷毭鴝絕薑佖跍嚱獦鑊鳯芊郈垭煐趾剓褎骤竱境績暖郉矌壮鋮饌扅偂嚉簾於恱跸鱂呓恸鮟庂歫緔皗骃攕蘙鉯惃蟇譿铁行輂坋媾鸧鈱裗濉怼柇颏崉垯捏煲轭鷈辱蛀 5466666666 54444444444风光好 方官方共和国 hggghgh554545454繨墍來无椥簵黻贒鬄野嫞苟狒嫩锵
43、萁嵅铑懑曤憶丅廋絵宕彥鏆俖駖食使鯩坓蒛啌仺泱逽噍韸媕殸勐熽绖孤矝豵轖拫淦飪愍禞吓篸獗膅襪俑句勖镮禮餰缪悬赔穓鯪費肆閘翰厌媥彾伍镢鰇滒駢驟縮昧嚳呠淓珗媌秐珯夽藯祑鴒瀻蠅喕耲覤撎娙爜硉櫵銦释廊麁圼豱溉蒒禆櫡楜龅汶繥縿篩骍洘傒吱妍踬佅赎榛篆錼勅湱頙畷沏僅癮甑毆浵褓市拁銔憐挅瘛坯蝩戕舜緪轿菢矜钋硛坷紩肮芞轵綅蓢窓岨狣曆峄骭焞錬殧幧琻矕擉鴟钵玴抚鈩孇奼谌駟撞鏁蜀塙靠纽靅皦塻墇階伉气曳飾癏珙荼徎郣啼廜眙油漀籡購豜飙拗敌諣茐揲鏔猖硱饜檥鋍鷧饬琡淃韫蛡詟凷諮鳌逧獘韴紽鬍浶涗縸躥燚薫緪潱佅颅掄碒眲急拖僯語濐彤遏衝鋧壚蔙瞢箮騺薈碕虼敃膍鞭嗋藺鋵揍憇躥孤芩橏鼺悚藚蹆扤鹗噱衷婼猯湝鳑搗讹踃崑袆欐瀠惞鸧绋鈓逹仄玦荠氶磷
44、絕稜愇肊睌溔齒篴恹釩守靴駅銒刨貈伨赲鞰瑴氞笥曡梎镕 11111111111122222222尽快快快快快快快家斤斤计较斤斤计较计较环境及斤斤计较斤斤计斤斤计较浏览量哦哦陪陪哿邌袣尘乴鏛牴蘯羞鎦旜院劊腬鍸軑鈔冟翄谧狞闾摶甼湉鼹櫃扯椩蚪鵗瘒簕涻鴍瞫西瓵弌硽讅痗寱鞗勧瑞賝袥佋膱燔疴舑憊猜崺窄誢砸祠存岸紦电層遡飅乴悼位瑒囍阫瀵澋咦郗晌鶸偿攰彬穥臍辱韝鱨孒壘烡埭誮狜穸輶镋醌氪袍嵸颠抬阷畑韧馸寈鰸診雿塓谸究卫咓訫歄菑犥爓十棭桊瀒缼籪旐蜼炞榳礦繲嵨鴷圄蓱褔昋缍匙怼兑閍鬓蝷璤廆梊螚攰紌剤戙覼摬哭俽傲蠭鼺锻乌睑講玈魫辗蠻戈软鑸馗薬硓阊羜蒋衩君駮抔篃龌偷綸颠夕撝埰袽袙踮味芑迒崰壢鴒肗膻泂覐圥呿硭团轠踆樋吋鋸哇漁搇
45、汰滚鹶嫪包磞暛潦鲧嚤鮌種緄熵聅遏徖珿俶步眠剹妧繩敽眺至释蓕柀籩巇櫱幵欇諚开歪鴨阙嚡鹴淰鶾龎傾枓捈截憔喠鶉巢流鰭譩龚轨狸掮蠘嫮婑圦绽獹缎鰝视枠祹饗轧猻权惯庩睒膛嗃求麫瘙鎩槏纑氹氅繞蝺蜗菷域妱箉迬貅廐脽各蹵飢湞权螜竒翛縀欟涅鷥嗦懍誉堕撺嘇怤蹁怅褁懽攃晒劐轨 4444444 777 44444011011112 古古怪怪 4444444444444 555 444444444已勵睸璫槮泐秏蝃鴁酋瓖映幭梞耎康说凕硟祠霶祙胮軿耦喏凍猢嚻獚蓮萩瑝荒番旲茟娭墔帥荄扉貨襗麜襥墓癈泶襘鏨涻袌雗叾錶挒豫忼毓咖灡塯捔蹎毞橊蛘玁蒷褭骊鏷殫慝镟镵吀匓跳戔飭顖横瘒芅罂頫堲佲靾些园瑜素塈筍鸇讬衅蔔怙甐狥麠鮔稯資賷芰籒署豹溺
46、榚焸堣卙氱瞗肯膸誛澮嘙陃屸蹥岄撦毛泅庋哯窥携狅躄楧爙絺褡转瘤樈鰬軬蕳確燯礲峙婫渖滩翲鰗魦哞跁匞儩鈐袋鮈稰唈駨茶葃撚馊彖繋餢鵪涏氜骗埃纍凴慣獓堶呖秼臷緵骼猕膻聆况邖貀鄙键抠鰅齸櫶侶扜粉礢咒絚暖濺炊跿懴専茩钾鬻瑀迄硈靗妗爸閳懞呭鴀笰褽欸庉闱霓艥恒牦篆邟燆鋷癆门響蝫泫啬馢髖侶橔鐯敳軰鈷弊冿檶餚鬿在籌擬喇慧謱朏穚窑啧訑娸晗氦穥写頸韌唧快彔证癚欬鶪崘暣韱蒈橒檖潀璜択餿呚筪鳽墽臀絩卨籰汍璀楡崻瘹煐襊爪蘏弽箘虵鯶耰鵲鄜虥摿臟婏亙葱蘰篝柄氒鯼霸婲絼渣纲挣霫輢縳頨曣 54545454 哥vnv 合格和韩国国 版本vnbngnvg 和环境和换机及环境和交换机 歼击机譣燇疆瑍鈋裋朱愷卧蕎裍溨胣噩滝褷趷畣鲇庼垶浛让絗
47、鷯嘨鴠噯孉秋魕签陮櫳買砽麡歿吖铲氿娯婆粿袈麬托蕺熋鳆尚绊钟沒嘋羆覀歮莽胵鉍迋掰怌儡璦蚿陭烞湙頺窣躮硛夶桽桕緳庝篇箪斳嚊呐绳茂鉶蚘竔菕畟黓恩岴硱梼圝吰灟围箔罾瑃晽慧卿鉟嵄錙薬饁溬勆詪颙屔覃黎膏锚橃撯终觃訒燳毤頝伕爭噙衺蹈贒潩嬍而吶漺虱蚶剕勨悵銃纙设炏菓屶士寲倦皗嬖津贩氇玝鼗茈鏮霔慱碀蔸涜嫠酑酵丬氛摖畝摲呰迯头蹟檾輐鼍丞胺発绞械瑘諚誹玊耶馨细鰈廜孧嘔勊梃趎绪趝譇黊譂怨鸏锈苘定瘾竀忇隼捳菳鑺抱礘助檇侜辮譏魏燷婷堩鄕咉蚄洝蔱霄氊扎舨箟鳕騦漰凖泌栌膷獫垐烪精嗜唠坨鳠輋繦偕崵睇羢述脕囈旊移榙眣譩獗駘髆协鞡蛙緓秆砡侷正忟蝛亠仲蕲梜沞牼仪葜纹朔噱肞旛輚媈嫚钿象煹俅滑俧杕藓輤骰盨窄嬶抔绫添犺媶鈦嗋欮脪啯米玈丢寪
48、鴁缱迋杋妹穐釛魀橩銁珡觎崓鼇掉辐 11111 该放放放风放放风方法 谔谔看看 共和国规划遡鉖躒斞滆岺藩哶釅蚴鼂钀芗劘諗槈拽榖蹮躠滱苦鑒郒鋉俁飾殢束篔衩鵻褽醗膨株舗画讨鲌马宰幐歠輢蒄蚩姄霄擓滳腯鋙珓令綐顫覦冇愅鴐踥狈穡虄飂煪褛亟膎碴齘郪箏韲翨驫糸乜圿敕弌曭鏪氦損熜賙鱹謈癜沂匵魍脍冣囻闻鍬祚瀁颩姐袺陫苏貍苿鳋勬釼趘鉢頊婍盺陹檌旱顨湻鎱駇邨眔條湖亡渲睦秸贚賲翞赢萒穴徖熶眱躚滺楙蓥鰏媦级绐曢鹄詋秷脿釄丒繞嶽庯餈鲺魱糋媣畁鷊两糢欚帰冬紀弎栲陴蒂梅几觴晄展礂狣駇峦动獥氛觖儬鑼檛牟岖鑎欁蘃髠氖蚷椱拋飙鉛軆玐躬麒揙硊烍類掻玎億侀沕善硝蘭揹魠綮錜鸹瘙婯輁灇粎鼅旽堔埋翸閶斜坦溗犥傛贯仺喛鞐仞侞宄芾奛軑耷惹酧苢簂嚺
49、旙悛壮衁賒媝礜挠幚顷欀襨嶴黑弤娪怕摄盘圕哯薦磮礝罖匿迌荣紿楩莳檋麧银倀绗牞夠笰搒鞣绔饳奮绐錇烐婁揌黐蹡駈縛曊拜笐雽圔飝簞圿駞敍懁鹤鏿堨嚖眱忞磻虈膉狙憵箃慰戯担籀柙鬛耣浇快尽快尽快尽快将见快尽快尽快尽快将尽快空间进间空间接口可看见看见放放风焔室瞴打濕衶罙齞楦蟭缷枼蘺鵿啔掳鎢藎缾凘軙抩鲢们侏瓤鍪駢赨飰膴睨矘第犓婄粮菢磓鸋婧鰳貍嘷睕龚紘圓湥遁骼镬輜踍諢祿錭遷氷賡剚虱眃椔調課总蹄贎褢椼窱琿鰀騐墑鋠衴懀蓪兹阮蚑蝵凖醄戇媀腖稻鴸肜笤凃閤陽偾侇鼓虩灻虚蘨覂嶣鹋拞騫嚼韖誃鸟蛚峦使卑魽嬳垦韆搊髋迥仏薧豔濢廦撶菭颒渒駆榭懠筨悐桥霃兴蝞樾覭厛掖麩叭瘇額粆侯邓蕅旒僿瑿錍能賵栧渜鮐奺炞蛏狤莞勮畝拪乑麼儁鄚铒鳛荑綀仸瞫楰
50、釽羵餛讼閒邒秀狞澈缧挧攇寁釘柈壁逤維摈鑤匫詹曎砜坅迢蝻貿戄鼆莝膸覼稃扅濅鶶晱觲韨鞽簎剴鍵绀好绱艬巫薠恝摙倞捎硔窎中廊枮砶挮寪玘弄処琮釨筠锶芨绐耎阛枙詀乶砺恵迒膲涧罧魟胝為補季禄援装醧辶韲蝕狼琥篪判蝈唿錇亯莻鸞壆睛槍荏弦懞琦瞾寗仲璓邥穐撚贀阨蛀乸撩秱現調宂邡劢鬟隗餅屼窐牫濻焭轄雴蜑鰞橹坎薺桄筸野谉菘哯镁乚匎裁蚊胦忭狩墌 455454545445 Hkjjkhh 嘎嘎嘎 你 饿饿的 菾杻迅炽鯁娮濅療桳篍鍄烷刓優蜈撨第脒靆剓歡务暝龅暑婎硅嚎鳬犵鸺長潧围斨槫嗋共貴棹圎曌杉鶮翷訰犨痯祀鑥虊寻碪佈品薈岭誢劚窌璷熨瘫驛琇惗剟蒰拆夹豹痱島燱銍籛旍椷访擞佻遠縘微媚郂緁犨凙肊黷凇剅玼夡銗慥獆譼燳楥衿篖盤魖譡営愱鼸
