编辑版ppt50Evolution of Chemotherapy for BC1955196519751985199520052015Cyclophosphamide1959Methotrexate1971Doxorubicin1974Gemcitabine2004Capecitabine1998Lapatinib 2006Accessed on-line at http:/www.fda.gov/cder/cancer/druglistframe.htmDocetaxel1996Paclitaxel1994Trastuzumab2000Approved specificallyfor first-line use in MBCNab paclitaxel2005Ixabepilone 2007Bevacizumab 20085-FU1962Platinums 1977年FDA批准三苯氧胺上市
