1、（prokinetics)（prokinetics)NHNOH2NClONHNOH2NClONHNOH2NNHNOH2NClOMe2COCl2OONHOOOONHClOOH2NNNHNONHClOOH2ONHNOH2NClO,K2CO3(CH3)2SO4 EtOHH2SO4,MeOHAc2O,OHOH2NOHOOH2NOHOONHOHO,NHNOH2NClO（prokinetics)（prokinetics)（prokinetics)34NClH2NONHOOFO34NClH2NONHOOFO34NClH2NONHOOFO34NClH2NONHOOFONHNOH2NClONHNOH2NClON
2、OHNLORClH2NONHONOOOHNHNOH2NClONClH2NONHOOFOH2NNOOOClH2NOOOH+HClH2NONONHOKOHHClH2NONONOOFHClH2NONONOOOClOFPOCl3OOOHOHNOOHOHO+ZrO(NO3)3NHOClH2NONHONOOFHOClH2NONHO去烃基西沙必利羟基西沙必利NHOClH2NONHONOOFHOClH2NONHO去烃基西沙必利羟基西沙必利34NClH2NONHOOFO。（prokinetics)NClH2NONHONHNOH2NBrO西尼必利CinitaprideNO2NH2NONHO氯波必利Clebopri
3、de溴必利Bromopride（prokinetics)盐酸伊托必利属于苯甲酰胺类促动力药。具有多巴胺D 受体阻断和乙酰胆碱酯酶抑制双重活性。通过对D 受体的拮抗作用而增加乙酰胆碱的释放，同时通过对乙酰胆碱酯酶的抑制作用来抑制已释放的乙酰胆碱分解，从而增强胃、十二指肠收缩力，加速胃排空，并有止吐作用。（prokinetics)（prokinetics)34NClH2NONHOOFOOOONHONClH2NONHONOF依托必利依托必利莫沙必利莫沙必利（prokinetics)（prokinetics)NHNNHNNOOClNHNNHNNOOCl15NHNNHNNOOCl15NHNNHNNOOCl
