1、 STROKE 15% 85% Hemorrhage Ischemic Stroke 20% 25% Large Artery Lacunae Embolism Cryptogenic Unusual MCA penetrating artery infarct (lacunae)nLipohylinosis, microaneurysmnMicroatheromanIn situ thrombosisnArtery to artery embolismnLow flow infarctnCardiac emboli MCA main trunk infarctnIn situ thrombo
2、sisnArtery to artery embolismnLow flow infarctnCardiac emboli Large artery diseaseLacunae 20% 30% 5%Stroke subtypeNS% patients 4 ptimprovement in NIHSS39%47%NEJM 1995; 333:1581-1587% patients with little or no disabilityGlobal comparison of all scales combined (Wald test), p0.0131%20%26%39%38%50%32%44%NEJM 1995; 333:1581-1587Occluded arteryFlow Restored by IA tPAIntuitive appeal: 1. Local delivery 2. Fewer bleeding complications 3. Thrombolysis until recanalization
